148625-90-5

Basic information

• Product Name: (1E,4E)-1-(3-Methoxy-4-methoxymethoxy-phenyl)-5-(4-methoxymethoxy-phenyl)-penta-1,4-dien-3-one
• Synonyms: (1E,4E)-1-(3-Methoxy-4-methoxymethoxy-phenyl)-5-(4-methoxymethoxy-phenyl)-penta-1,4-dien-3-one
• CAS NO: 148625-90-5
• Molecular Weight: 384.429
• Mol File: 148625-90-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1E,4E)-1-(3-Methoxy-4-methoxymethoxy-phenyl)-5-(4-methoxymethoxy-phenyl)-penta-1,4-dien-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1E,4E)-1-(3-Methoxy-4-methoxymethoxy-phenyl)-5-(4-methoxymethoxy-phenyl)-penta-1,4-dien-3-one(148625-90-5)
• EPA Substance Registry System: (1E,4E)-1-(3-Methoxy-4-methoxymethoxy-phenyl)-5-(4-methoxymethoxy-phenyl)-penta-1,4-dien-3-one(148625-90-5)

Safety Data

• Hazardous Substances Data: 148625-90-5(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 123-08-0 4-hydroxy-benzaldehyde 
• 5533-00-6 3-methoxy-4-methoxymethoxy-benzaldehyde 
• 6515-21-5 4-methoxymethoxy-benzaldehyde 
• 52328-99-1 1-(3-methoxy-4-methoxymethyloxyphenyl)-(1E)-1-buten-3-one 

Relevant articles and documents

ANTI-OXIDATIVE AND ANTI-INFLAMMATORY CURCUMIN-RELATED PHENOLICS FROM RHIZOMES OF CURCUMA DOMESTICA

Two new natural phenolics were isolated from the rhizomes of Curcuma domestica along with four known curcuminoids.The structures of the former were determined to be 1,5-bis(4-hydroxy-3-methoxyphenyl)penta-(1E,4E)-1,4-dien-3-one and 1-(4-hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl)-penta-(1E,4E)-1,4-dien-3-one, respectively, by spectral data and syntheses.Anti-oxidant activity of the phenolics was determined by the inhibition of autoxidation of linoleic acid in a water-alcohol system.Anti-inflammatory activity of the isolated compounds was determined on mouse ears by using a tumour promoter, TPA (12-O-tetradecanoylphorbol-13-acetate) as an inducer. Key Word Index: Curcuma domestica; Zingiberaceae; rhizome; curcuminoid; phenolic; anti-inflammatory activity; antioxidant activity.