1486520-96-0

Basic information

• Product Name: 12-(4-fluorobenzyl)-6-thioxo-11b,12-dihydro-6H-quinazolino[3,4-a]quinazolin-13(7H)-one
• Synonyms: 12-(4-fluorobenzyl)-6-thioxo-11b,12-dihydro-6H-quinazolino[3,4-a]quinazolin-13(7H)-one
• CAS NO: 1486520-96-0
• Molecular Weight: 389.453
• Mol File: 1486520-96-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 12-(4-fluorobenzyl)-6-thioxo-11b,12-dihydro-6H-quinazolino[3,4-a]quinazolin-13(7H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 12-(4-fluorobenzyl)-6-thioxo-11b,12-dihydro-6H-quinazolino[3,4-a]quinazolin-13(7H)-one(1486520-96-0)
• EPA Substance Registry System: 12-(4-fluorobenzyl)-6-thioxo-11b,12-dihydro-6H-quinazolino[3,4-a]quinazolin-13(7H)-one(1486520-96-0)

Safety Data

• Hazardous Substances Data: 1486520-96-0(Hazardous Substances Data)

Upstream product

• 140-75-0 para-fluorobenzylamine 
• 75-15-0 carbon disulfide 
• 1486520-86-8 C₂₁H₁₈FN₃O 
• 1486520-79-9 C₂₁H₁₆FN₃O₃ 
• 118-48-9 isatoic anhydride 
• 827006-84-8 2-amino-N-(4-fluorobenzyl)benzamide 

Relevant articles and documents

Novel four-step synthesis of thioxo-quinazolino[3,4- A ]quinazolinone derivatives

A novel synthesis of thioxo-quinazolino[3,4-a]quinazolinone framework was developed through a four-step reaction starting from isatoic anhydride. The resulting 2-aminobenzamides from the reaction of isatoic anhydride and different amines underwent coupling-cyclization reaction with 2-nitrobenzaldehydes, reduction of nitro group, and then cyclization reaction with carbon disulfide (CS2). All steps were carried out under easy and user-friendly conditions in a short time without using expensive catalysts or reagents. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.]