148672-58-6Relevant articles and documents
Identification of a potent and selective 5-HT1B receptor antagonist
Wyman, Paul A.,Marshall, Howard R.,Flynn, Sean T.,King, Ron J.,Thompson, Mervyn,Smith, Paul W.,Hadley, Michael S.,Price, Gary W.,Scott, Claire M.,Dawson, Lee A.
, p. 4708 - 4712 (2007/10/03)
An SAR study around the mixed 5-HT1ABD receptor antagonist SB-272183 found that introduction of cis-2,6-dimethyl substitution onto the piperazine ring was a key structural change, which imparted a combination of both excellent selectivity over
