148934-66-1 Usage
Description
Methyl 3-chloro-1-methyl-1H-pyrazole-4-carboxylate is a chlorinated derivative of pyrazole with the molecular formula C6H7ClN2O2. It is a chemical compound known for its diverse biological activities, such as antimicrobial, anti-inflammatory, and antifungal properties. This versatile intermediate is widely used in the synthesis of pharmaceuticals and agrochemicals, making it a valuable component in various industries.
Uses
Used in Pharmaceutical Industry:
Methyl 3-chloro-1-methyl-1H-pyrazole-4-carboxylate is used as an intermediate for the synthesis of various pharmaceuticals. Its diverse biological activities, including antimicrobial, anti-inflammatory, and antifungal properties, make it a promising candidate for the development of drugs to treat a wide range of diseases and disorders.
Used in Agrochemical Industry:
Methyl 3-chloro-1-methyl-1H-pyrazole-4-carboxylate is used as an intermediate in the production of pesticides and herbicides. Its ability to inhibit the growth of certain microorganisms and pests makes it a valuable component in the development of effective and environmentally friendly agrochemicals.
Used in Antimicrobial Applications:
Methyl 3-chloro-1-methyl-1H-pyrazole-4-carboxylate is used as an antimicrobial agent for its ability to inhibit the growth of certain microorganisms. This property makes it suitable for use in various applications, such as in the development of antibiotics and antifungal medications.
Used in Anti-inflammatory Applications:
Methyl 3-chloro-1-methyl-1H-pyrazole-4-carboxylate is used as an anti-inflammatory agent due to its ability to reduce inflammation. This property can be utilized in the development of medications for treating various inflammatory conditions.
Used in Antifungal Applications:
Methyl 3-chloro-1-methyl-1H-pyrazole-4-carboxylate is used as an antifungal agent for its ability to inhibit the growth of fungi. This makes it a potential candidate for the development of antifungal drugs to treat fungal infections.
Check Digit Verification of cas no
The CAS Registry Mumber 148934-66-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,9,3 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 148934-66:
(8*1)+(7*4)+(6*8)+(5*9)+(4*3)+(3*4)+(2*6)+(1*6)=171
171 % 10 = 1
So 148934-66-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H7ClN2O2/c1-9-3-4(5(7)8-9)6(10)11-2/h3H,1-2H3
148934-66-1Relevant articles and documents
Synthesis of Halosulfuron-methyl via Selective Chlorination at 3- and/or 5-Position of Pyrazole-4-carboxylates
Morimoto, Katsushi,Sato, Toshiaki,Yamamoto, Susumu,Takeuchi, Hiroshi
, p. 537 - 540 (2007/10/03)
Reactions of methyl pyrazole-4-carboxylates 4b-d with N-chlorosuccinimide under heating conditions without a solvent gave methyl 3,5-dichloro-1-methylpyrazole-4-carboxylate 4a in good yields. The reaction of 4a with sodium hydrosulfide led to a nucleophilic substitution on the 5-position regioselectively to afford methyl 3-chloro-1-methyl-5-mercaptopyrazole-4-carboxylate 6a, which was followed by oxidative chlorination and amination to obtain 3-chloro-1-methyl-5-sulfamoylpyrazole-4-carboxylate 2a. Finally, the reaction of 2a with phenyl 4,6-dimethoxypyrimidin-2-yl carbamate 7 provided methyl 3-chloro-5-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-1-methylpyrazole-4- carboxylate (halosulfuron-methyl) 1a promising herbicide in corn.
