14901-29-2Relevant articles and documents
Regioselective synthesis of oxepinones and azepinones by gold-catalyzed cycloisomerization of functionalyzed cyclopropyl alkynes
Fernandez-Garcia, Jesus M.,Garcia-Garcia, Patricia,Fernandez-Rodriguez, Manuel A.,Perez-Anes, Alexandra,Aguilar, Enrique
, p. 11185 - 11187 (2013)
A regioselective synthesis of oxepinones and azepinones in good to excellent yields from alkynylcyclopropanecarboxylic acid derivatives is described. This novel cycloisomerization cascade process consists of a nucleophilic addition followed by a cyclopropane ring-opening, where both donor and acceptor groups are required as substituents of the cyclopropane ring.
An Efficient Synthesis of Acetylenic γ- and δ-Hydroxy Ketones, γ- and δ-Keto Acids, and γ-Diketones via Addition of 1-Alkinyllithium Compounds to γ- and δ-Lactones
Wedler, Christine,Schick, Hans
, p. 410 - 414 (2007/10/02)
2-Hydroxy-6-alkyn-5-ones 3, 1-hydroxy-5-alkyn-4-ones 4, and 1-hydroxy-6-alkyn-5-ones 5 are conveniently obtained in exellent yields through a highly selective monoaddition of an 1-alkynyllithium compound 2 to γ-valerolactone (1a), γ-butyrolactone (1b) or
