149050-17-9

Basic information

• Product Name: 1-(4-chlorophenyl)cyclobutylmethyl chloride
• CAS NO: 149050-17-9
• Molecular Weight: 215.122
• Mol File: 149050-17-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-chlorophenyl)cyclobutylmethyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)cyclobutylmethyl chloride(149050-17-9)
• EPA Substance Registry System: 1-(4-chlorophenyl)cyclobutylmethyl chloride(149050-17-9)

Safety Data

• Hazardous Substances Data: 149050-17-9(Hazardous Substances Data)

Upstream product

• 140-53-4 p-chlorobenzyl cyanide 
• 50921-39-6 1-(4-chlorophenyl)cyclobutane-1-carboxylic acid 
• 28049-61-8 1-(4-chlorophenyl)cyclobutanecarbonitrile 

Downstream Products

• 149050-22-6 C₁₁H₁₂Cl₂Mg 

Relevant articles and documents

A polar substituent effect on the ring-cleavage rearrangement of 1-arylcyclobutylmethyl Grignard reagents

The kinetics of the ring-cleavage rearrangements of 1-phenylcyclobutylmethylmagnesium chloride and its p-methyl and p-chloro analogs have been determined.The first-order rate constants are correlated by the Hammett equation, with ρ=-0.47.The results are consistent with a concerted mechanism with a cyclic transition state having significant polar character, although polar effects on the stabilities of reactant and product may also contribute.The phenyl group itself slows the reaction by a factor of 0.031, which is interpreted principally in terms of steric destabilization of the transition state.