14908-53-3Relevant articles and documents
One-pot reduction of carboxylic acids via O-acylisoureas
Herbert, John M.,Hewson, Alan T.,Peace, James E.
, p. 823 - 832 (1998)
A simple one-pot reduction of aliphatic carboxylic acids to primary alcohols, by treatment with dicyclohexylcarbodiimide followed by lithium borohydride, is reported. The same methodology applied to aromatic carboxylic acids is shown to give a mixture of the alcohols with N- cyclohexylcarboxamides.
Synthesis of stable 1H-azirines reinvestigated: A structural corrigendum
Banert, Klaus,Hagedorn, Manfred,Peisker, Heiko
supporting information, p. 2943 - 2946 (2013/02/25)
The isoquinoline-catalyzed synthesis of pretended 1H-azirines from phenacyl bromides and N,N-dialkylcarbodiimides was repeated. The products do not possess the structure of antiaromatic 1H-azirines, but simple N-acyl-N,N-dialkylureas were formed instead. This structural corrigendum was confirmed by the independent synthesis of the known ureas and comparison of their 1H NMR and 13C NMR spectroscopic data in the case of six compounds. Thus, 1H-azirines keep their classification as very short-lived intermediates. Georg Thieme Verlag KG · Stuttgart · New York.
Formation of N-acyl-N,N'-dicyclohexylureas from DCC and arenecarboxylic acids in the presence of hydroxybenzotriazole in CH2CI2 at room temperature
Kaiser, Carlos R.,Pinheiro, Alessandra C.,De Souza, Marcus V. N.,Wardell, James L.,Wardell, Solange M.S.V.
experimental part, p. 468 - 472 (2009/08/15)
The syntheses of N-acyl-N',N'-dicyclohexylureas from 1,3- dicyclohexylcarbodiimide and arenecarboxylic acids [p-XC6H 4CO2H (X = H or NO2), 2-, 3- or 4-pyridinecarboxylic acid and pyrazinecarboxylic acid] in the
