149553-65-1

Basic information

• Product Name: 2-(2,2-diphenylethyl)-3-isopropylidene-5,5-dimethylpyrrolidine
• CAS NO: 149553-65-1
• Molecular Weight: 319.49
• Mol File: 149553-65-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2,2-diphenylethyl)-3-isopropylidene-5,5-dimethylpyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2-diphenylethyl)-3-isopropylidene-5,5-dimethylpyrrolidine(149553-65-1)
• EPA Substance Registry System: 2-(2,2-diphenylethyl)-3-isopropylidene-5,5-dimethylpyrrolidine(149553-65-1)

Safety Data

• Hazardous Substances Data: 149553-65-1(Hazardous Substances Data)

Upstream product

• 7474-19-3 3,3-diphenylpropionamide 
• 606-83-7 3,3-Diphenylpropionic acid 
• 2286-54-6 3,3-diphenyl-propionitrile 
• 110-03-2 2,5-dimethyl-2,5-hexanediol 
• 149553-59-3 2-(2,2-diphenylethyl)-3-isopropylidene-5,5-dimethyl-1-pyrroline 

Relevant articles and documents

Agents for the treatment of overactive detrusor. IV. Synthesis and structure-activity relationships of cyclic analogues of terodiline

A series of pyrrolidine derivatives were synthesized and examined for inhibitory activity on detrusor contraction in vivo. Among those compounds, 5,5-dimethyl-2-(2,2-diphenylethyl)-3-isopropylidenepyrrolidine hydrochloride (41 · HCl), 2-(2,2-di(4-fluorophenyl)ethylene)-5,5-dimethyl-3-isopropylidenepyrrol idine hydrochloride (42 · HCl), (+)5,5-dimethyl-2-(N,N-diphenylaminomethyl)-3-isopropylidenepyrrolidin e hydrochloride (+)-(43a · HCl),(-)-5,5-dimethyl-2-(N,N-diphenylaminomethyl)-3-isopropylidenepyrr olidine hydrochloride (-)-(43a · HCl), and 2-(N,N-di(4-fluorophenyl)aminomethyl)-5,5-dimethyl-3-isopropylidenepyr rolidine methanesulfonate (43b · MsOH) showed stronger inhibitory activity on detrusor contraction than terodiline.