14960-81-7

Basic information

• Product Name: 3-methyl-9H-carbazol-1-ol
• Synonyms: 3-methyl-9H-carbazol-1-ol
• CAS NO: 14960-81-7
• Molecular Weight: 197.236
• Mol File: 14960-81-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 3-methyl-9H-carbazol-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-9H-carbazol-1-ol(14960-81-7)
• EPA Substance Registry System: 3-methyl-9H-carbazol-1-ol(14960-81-7)

Safety Data

• Hazardous Substances Data: 14960-81-7(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 1477-50-5 Indole-2-carboxylic acid 
• 1015760-82-3 (E)-N-(2-(3-oxobut-1-en-1-yl)phenyl)benzenesulfonamide 
• 151721-32-3 N-benzenesulfonyl-o-aminobenzaldehyde 
• 74204-00-5 3-bromo-5-methylphenol 
• 796061-07-9 4-methyl-N-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzenesulfonamide 
• 29578-83-4 3-bromo-5-methoxytoluene 
• 100-63-0 phenylhydrazine 
• 6933-54-6 3-methyl-2,3,4,9-tetrahydro-1H-carbazole 
• 103763-38-8 4,5-dihydro-3-indol-2-ylcarbonyl-4-methylfuran-2-one 
• 103763-41-3 4-hydroxy-1-indol-2-yl-3-methylbutan-1-one 
• 103763-45-7 1-indol-2-yl-3-methylbutane-1,4-dione 
• 1202-04-6 indole-2-carboxylic acid methyl ester 
• 182261-83-2 methyl 1-hydroxy-9H-carbazole-3-carboxylate 

Downstream Products

• 100108-66-5 murrayaquinone A 
• 155519-86-1 bismurrayaquinone A 
• 4532-33-6 1-methoxy-3-methylcarbazole 

Relevant articles and documents

A short divergent approach to highly substituted carbazoles and β-carbolines via in situ-generated diketoindoles

Based on an aza-alkylation/Michael addition cascade reaction developed by Kim and co-workers we have developed divergent cascade reactions leading to either highly substituted 1-hydroxycarbazoles, 3-hydroxycarbazoles or β-carbolines, starting from readily

Divergent Syntheses of Carbazole Alkaloids

Starting from common intermediate methyl 1-hydroxy-9 H -carbazole-3-carboxylate, synthetic routes toward murrayaquinone A, olivacine, and N -methylcalothrixin B were developed.

Synthesis of substituted carbazoles and β-carbolines by cyclization of diketoindole derivatives

A new route to substituted β-carbolines and carbazoles is described. Diketoindole intermediates, prepared by Friedel-Crafts acylations of 3-substituted indoles, have been converted to 3-hydroxycarbazoles and β-carbolines in good yields, 51-96% and 82-97%, respectively. This method also allows for the formation of 4-substituted β-carbolines. The application of this methodology to the synthesis of the natural products hyellazole and 6-chlorohyellazole is also described.