149606-97-3

Basic information

• Product Name: (S)-tert-butyl 2-((1R,2R)-3-(benzyloxy)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
• Synonyms: (S)-tert-butyl 2-((1R,2R)-3-(benzyloxy)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
• CAS NO: 149606-97-3
• Molecular Formula: C₂₁H₃₁NO₅
• Molecular Weight: 377.47454
• Mol File: 149606-97-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 476.8±20.0 °C(Predicted)
• Appearance: /
• Density: 1.111±0.06 g/cm3(Predicted)
• PKA: -2.22±0.40(Predicted)
• CAS DataBase Reference: (S)-tert-butyl 2-((1R,2R)-3-(benzyloxy)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 2-((1R,2R)-3-(benzyloxy)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate(149606-97-3)
• EPA Substance Registry System: (S)-tert-butyl 2-((1R,2R)-3-(benzyloxy)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate(149606-97-3)

Safety Data

• Hazardous Substances Data: 149606-97-3(Hazardous Substances Data)

Usage

Description

(S)-tert-butyl 2-((1R,2R)-3-(benzyloxy)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate is a complex pyrrolidine derivative with the molecular formula C22H31NO5. It features a tert-butyl ester group and a benzyloxy substituent, which contribute to its structural complexity and potential for various applications. (S)-tert-butyl 2-((1R,2R)-3-(benzyloxy)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate is synthesized from the reaction of (R)-3-((tert-butoxycarbonyl)amino)-2-methyl-1-oxopropyl benzoate and L-methionine, with the formation of a new carboxylate and the protection of the amino group of the starting material.

Uses

Used in Organic Synthesis:
(S)-tert-butyl 2-((1R,2R)-3-(benzyloxy)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate is used as an intermediate in organic synthesis for the creation of various complex molecules. Its unique structural features and functional groups make it a valuable building block for the development of new compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (S)-tert-butyl 2-((1R,2R)-3-(benzyloxy)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate is used as a key component in the development of drugs and biologically active molecules. Its potential medical applications are being explored due to its structural features and functional groups, which may contribute to the creation of novel therapeutic agents.
Used in Drug Development:
(S)-tert-butyl 2-((1R,2R)-3-(benzyloxy)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate is utilized in drug development as a precursor to synthesize potential pharmaceutical compounds. Its versatility in chemical reactions allows for the creation of a wide range of drug candidates with various therapeutic targets.

Upstream product

• 186581-53-3 diazomethane 
• 163768-51-2 benzyl (2R,3R,2'S)-3-(N-tert-butoxycarbonyl-2'-pyrrolidinyl)-3-hydroxy-2-methylpropanoate 
• 74-88-4 methyl iodide 
• 122-63-4 benzyl proprionate 
• 69610-41-9 Boc-L-Pro-H 
• 100-39-0 benzyl bromide 
• 120205-50-7 N-Boc-(2R,3R,4S)-dolaproine 
• 1369427-40-6 (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropionic acid dicyclohexylamine salt 
• 133645-51-9 (4R,5S,2'R,3'R,2S)-3-[3'-(N-tert-butoxycarbonyl-2-pyrrolidinyl)-3-hydroxy-2'-methylpropanoyl]-4-methyl-5-phenyl-2-oxazolidinone 
• 100-44-7 benzyl chloride 
• 180715-99-5 (4R,5S,2'R,3'R,2S)-3-[3'-(N-tert-butoxycarbonyl-2-pyrrolidinyl)-3'-methoxy-2'-methylpropanoyl]-4-methyl-5-phenyl-2-oxazolidinone 
• 100-51-6 benzyl alcohol 

Downstream Products

• 120205-50-7 N-Boc-(2R,3R,4S)-dolaproine 
• 130272-98-9 (S)-N-{(S)-1-[((1S,2S)-1-((S)-sec-Butyl)-2-methoxy-4-{(S)-2-[(1R,2R)-1-methoxy-2-((S)-2-phenyl-1-thiazol-2-yl-ethylcarbamoyl)-propyl]-pyrrolidin-1-yl}-4-oxo-butyl)-methyl-carbamoyl]-2-methyl-propyl}-2-dimethylamino-3-methyl-butyramide 
• 120205-54-1 tert-butyl (2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]pyrrolidine-1-carboxylate 
• 110417-88-4 dolastatin 10 
• 173441-24-2 Z-Val-Val-Dil-Dap-Doe 
• 173441-25-3 Z-N-Me-Val-Val-Dil-Dap-Doe 
• 203849-91-6 N-Me-Val-Val-Dil-Dap-Doe 

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