1497411-35-4Relevant articles and documents
Enantioselective, nickel-catalyzed suzuki cross-coupling of quinolinium ions
Shields, Jason D.,Ahneman, Derek T.,Graham, Thomas J. A.,Doyle, Abigail G.
supporting information, p. 142 - 145 (2014/01/23)
Quinolinium ions are engaged in an asymmetric, Ni-catalyzed Suzuki cross-coupling to yield 2-aryl- and 2-heteroaryl-1,2-dihydroquinolines. Key to the development of this method is the use of a Ni(II) precatalyst that activates without the need for strong reductants or high temperatures. The Ni-iminium activation mode is demonstrated as an exceptionally mild pathway to generate enantioenriched products from racemic starting materials.