149765-17-3

Basic information

• Product Name: diethyl N-<2-pivaloylamino-4-chloro<(pyrrolo<2,3-d>pyrimidin-5-yl)ethynyl>benzoyl>-L-glutamate
• Synonyms: diethyl N-<2-pivaloylamino-4-chloro<(pyrrolo<2,3-d>pyrimidin-5-yl)ethynyl>benzoyl>-L-glutamate
• CAS NO: 149765-17-3
• Molecular Weight: 582.056
• Mol File: 149765-17-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: diethyl N-<2-pivaloylamino-4-chloro<(pyrrolo<2,3-d>pyrimidin-5-yl)ethynyl>benzoyl>-L-glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl N-<2-pivaloylamino-4-chloro<(pyrrolo<2,3-d>pyrimidin-5-yl)ethynyl>benzoyl>-L-glutamate(149765-17-3)
• EPA Substance Registry System: diethyl N-<2-pivaloylamino-4-chloro<(pyrrolo<2,3-d>pyrimidin-5-yl)ethynyl>benzoyl>-L-glutamate(149765-17-3)

Safety Data

• Hazardous Substances Data: 149765-17-3(Hazardous Substances Data)

Upstream product

• 116387-23-6 diethyl N-(4-ethynylbenzoyl)-L-glutamate 
• 149765-16-2 N-(4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl-propionamide 
• 7355-55-7 2-amino-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one 
• 149765-15-1 N-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl-propionamide 
• 137281-08-4 N-(4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-2-yl)pivalamide 
• 84955-31-7 4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 149765-20-8 diethyl N-<2-pivaloylamino-4-mercapto<(pyrrolo<2,3-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamate 
• 149765-18-4 diethyl N-<2-pivaloylamino-4-chloro<(pyrrolo<2,3-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamate 
• 149765-22-0 diethyl N-<2-pivaloylamino<(pyrrolo<2,3-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamate 
• 149765-24-2 diethyl N-<2-pivaloylamino<(5,6-dihydropyrrolo<2,3-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamate 

Relevant articles and documents

Design, synthesis, and biological activities of classical N-{4-[2-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl] benzoyl}-L-glutamic acid and its 6-methyl derivative as potential dual inhibitors of thymidylate synthase and dihydrofolate reductase and

Two novel analogues, N-{2-amino-4-ethyl[(pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid (2) and N-{2-amino-4-ethyl-6-methyl[(pyrrolo[2,3-d]pyrimidin-5-yl) ethyl]benzoyl}-L-glutamic acid (4), were designed and synthesized as potent dual inhibi