149820-74-6 Usage
Description
Xemilofiban is a synthetic GPIIb/IIIa receptor antagonist that functions as an antiplatelet agent. It is designed to inhibit platelet aggregation and is used in the medical field for various cardiovascular applications. Xemilofiban works by binding to the glycoprotein IIb/IIIa receptors on the platelet surface, thus preventing the cross-linking of fibrinogen and subsequent platelet aggregation.
Uses
Used in Cardiovascular Medicine:
Xemilofiban is used as an antiplatelet agent for the prevention of post-recanalization reocclusion of coronary vessels. It helps in maintaining the patency of the vessels after procedures such as angioplasty or thrombolysis, reducing the risk of reocclusion and further cardiovascular events.
Xemilofiban is also used as a therapeutic agent for the treatment of unstable angina. It helps in reducing the frequency and severity of anginal episodes by inhibiting platelet aggregation, which is a key factor in the development of thrombi that can obstruct blood flow in the coronary arteries.
Check Digit Verification of cas no
The CAS Registry Mumber 149820-74-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,8,2 and 0 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 149820-74:
(8*1)+(7*4)+(6*9)+(5*8)+(4*2)+(3*0)+(2*7)+(1*4)=156
156 % 10 = 6
So 149820-74-6 is a valid CAS Registry Number.
InChI:InChI=1/C18H22N4O4/c1-3-13(11-17(25)26-4-2)21-15(23)9-10-16(24)22-14-7-5-12(6-8-14)18(19)20/h1,5-8,13H,4,9-11H2,2H3,(H3,19,20)(H,21,23)(H,22,24)/t13-/m1/s1
149820-74-6Relevant articles and documents
A very short, efficient and inexpensive synthesis of the prodrug form of SC-54701A. A platelet aggregation inhibitor
Cossy,Schmitt,Cinquin,Buisson,Belotti
, p. 1699 - 1700 (1997)
A short and efficient synthesis of the prodrug form of SC-54701A has been achieved from (trimethylsilyl)acetylene in 6 steps with an overall yield of 19%.