149845-06-7 Usage
Description
Saquinavir mesylate, also known by its brand name Invirase (Roche), is a peptidomimetic hydroxyethylamine inhibitor primarily used to treat human immunodeficiency virus (HIV) infection. It is a white crystalline solid with potent antiviral properties, functioning as a selective HIV protease inhibitor.
Uses
Used in Pharmaceutical Industry:
Saquinavir mesylate is used as an antiviral agent for the treatment of HIV infection. It works by inhibiting the HIV protease enzyme, which is essential for the replication of the virus within host cells. By blocking this enzyme, the virus cannot multiply, thus helping to control the infection and slow down the progression of the disease.
Used in Research and Development:
Saquinavir mesylate is also used in cell signaling and immunology studies. It serves as a valuable tool for researchers to understand the mechanisms of HIV infection and the role of protease enzymes in the viral life cycle. This knowledge can be applied to develop new therapeutic strategies and improve existing treatments for HIV.
Hazard
Moderately toxic by ingestion.
Biochem/physiol Actions
Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy. It inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at saquinavir as a possible anti-cancer agent.
Check Digit Verification of cas no
The CAS Registry Mumber 149845-06-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,8,4 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 149845-06:
(8*1)+(7*4)+(6*9)+(5*8)+(4*4)+(3*5)+(2*0)+(1*6)=167
167 % 10 = 7
So 149845-06-7 is a valid CAS Registry Number.
InChI:InChI=1/C38H50N6O5.CH4O3S/c1-38(2,3)43-37(49)32-20-26-14-7-8-15-27(26)22-44(32)23-33(45)30(19-24-11-5-4-6-12-24)41-36(48)31(21-34(39)46)42-35(47)29-18-17-25-13-9-10-16-28(25)40-29;1-5(2,3)4/h4-6,9-13,16-18,26-27,30-33,45H,7-8,14-15,19-23H2,1-3H3,(H2,39,46)(H,41,48)(H,42,47)(H,43,49);1H3,(H,2,3,4)/t26-,27+,30-,31-,32-,33+;/m0./s1
149845-06-7Relevant articles and documents
NOVEL POLYMORPHS OF SAQUINAVIR
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Page/Page column 3, (2012/02/15)
The present invention provides novel polymorphs of saquinavir, processes for their preparation and pharmaceutical compositions comprising them. The present invention also provides a process for purification of saquinavir. The present invention further provides a novel process for preparation of known saquinavir crystalline form I.