14985-26-3 Usage
Description
(2S,3S)-2-(4-nitrophenyl)-3-phenyloxirane, also known as 2-(4-nitrophenyl)-3-phenyl-oxirane, is a chiral epoxide with the molecular formula C15H11NO3. It is a stereoisomer with two chiral centers and is commonly used as a building block in organic synthesis. (2S,3S)-2-(4-nitrophenyl)-3-phenyloxirane contains a 4-nitrophenyl group and a phenyl group attached to an oxirane ring, which imparts reactivity and stability to the molecule.
Uses
Used in Pharmaceutical Synthesis:
(2S,3S)-2-(4-nitrophenyl)-3-phenyloxirane is used as a key intermediate in the synthesis of pharmaceuticals for its reactivity and stability. Its unique structure allows for the creation of various drug molecules with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, (2S,3S)-2-(4-nitrophenyl)-3-phenyloxirane serves as an important building block for the development of new agrochemicals. Its properties make it suitable for the synthesis of pesticides and other agricultural chemicals that can improve crop protection and yield.
Used in Materials Science:
(2S,3S)-2-(4-nitrophenyl)-3-phenyloxirane is utilized in materials science for its potential applications in creating new materials with specific properties. Its reactivity and stability contribute to the development of advanced materials for various industries.
Used in Research Applications:
As a chiral epoxide, (2S,3S)-2-(4-nitrophenyl)-3-phenyloxirane is a valuable compound in research settings. It is used in various studies to explore its chemical properties, reactions, and potential uses in different fields, including the development of new synthetic methods and the investigation of its biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 14985-26-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,9,8 and 5 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 14985-26:
(7*1)+(6*4)+(5*9)+(4*8)+(3*5)+(2*2)+(1*6)=133
133 % 10 = 3
So 14985-26-3 is a valid CAS Registry Number.
14985-26-3Relevant articles and documents
Radical-mediated aerobic oxidation of substituted styrenes and stilbenes
Aman, Hasil,Chiu, Wei-Hua,Chuang, Gary Jing,Liu, Pin-Heng
supporting information, p. 20103 - 20106 (2021/12/02)
A 2,2-azobis(isobutyronitrile)-catalyzed oxidative cleavage of alkenes with molecular oxygen as the oxidant was described. Carbonyl compounds and oxiranes were obtained in moderate yield under mild conditions. This study provided useful insights into the mechanism of aerobic oxidative cleavage of alkenes.
One-pot synthesis of epoxides from benzyl alcohols and aldehydes
Alfonzo, Edwin,Mendoza, Jesse W.L.,Beeler, Aaron B.
supporting information, p. 2308 - 2312 (2018/09/14)
A one-pot synthesis of epoxides from commercially available benzyl alcohols and aldehydes is described. The reaction proceeds through in situ generation of sulfonium salts from benzyl alcohols and their subsequent deprotonation for use in Corey–Chaykovsky epoxidation of aldehydes. The generality of the method is exemplified by the synthesis of 34 epoxides that were made from an array of electronically and sterically varied alcohols and aldehydes.
The B(C6F5)3-Catalyzed Tandem Meinwald Rearrangement-Reductive Amination
Tiddens, Martine R.,Klein Gebbink, Robertus J. M.,Otte, Matthias
supporting information, p. 3714 - 3717 (2016/08/16)
A system of three coupled catalytic cycles enabling the one-pot transformation of epoxides to amines via Meinwald rearrangement, imine condensation, and imine reduction is described. This assisted tandem catalysis is catalyzed by B(C6F5)3 resulting in the first tandem Meinwald rearrangement-reductive amination protocol. The reaction proceeds in nondried solvents and yields β-functionalized amines. In particular, β-diarylamines are obtained in high yields.
