149929-78-2

Basic information

• Product Name: N-(3-(4,-Methoxyphenyl)-2-propynyl)-oxyphthalimide
• Synonyms: N-(3-(4,-Methoxyphenyl)-2-propynyl)-oxyphthalimide
• CAS NO: 149929-78-2
• Molecular Weight: 307.306
• Mol File: 149929-78-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(3-(4,-Methoxyphenyl)-2-propynyl)-oxyphthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-(4,-Methoxyphenyl)-2-propynyl)-oxyphthalimide(149929-78-2)
• EPA Substance Registry System: N-(3-(4,-Methoxyphenyl)-2-propynyl)-oxyphthalimide(149929-78-2)

Safety Data

• Hazardous Substances Data: 149929-78-2(Hazardous Substances Data)

Upstream product

• 37614-59-8 4-(4-methoxyphenyl)prop-2-yn-1-ol 
• 524-38-9 N-hydroxyphthalimide 
• 173019-85-7 3-bromo-1-(4-methoxyphenyl)propyne 
• 1972-28-7 diethylazodicarboxylate 
• 696-62-8 para-iodoanisole 

Downstream Products

• 1287768-71-1 benzyl (3-(4-methoxylphenyl)-2-propynyl)oxycarbamate 
• 1287768-89-1 isopropyl (3-(4-methoxyphenyl)-2-propynyl)oxycarbamate 
• 1287769-09-8 benzyl 2,5-dihydro-4-iodo-3-(4-methoxylphenyl)-2H-isoxazole-2-carboxylate 
• 1287769-22-5 4-iodo-3-(4-methoxylphenyl)isoxazole 
• 730926-74-6 O-(3-(4-methoxyphenyl)-2-propynyl)hydroxylamine 

Relevant articles and documents

Iodocyclization of hydroxylamine derivatives based on the control of oxidative aromatization leading to 2,5-dihydroisoxazoles and isoxazoles

An efficient method for the synthesis of 2,5-dihydroisoxazoles and isoxazoles using iodocyclization of N-alkoxycarbonyl O-propargylic hydroxylamines has been developed. 2,5-Dihydro-4-iodoisoxazole underwent the cross-coupling reactions without aromatization to afford polyfunctionalized 2,5-dihydroisoxazoles. This process was applied to the preparation of valdecoxib and its 2,5-dihydro-derivative.

OXIME AND AMINE SUBSTITUTED AZABICYCLO AND AZOCYCLO MUSCARINIC AGONISTS AND METHODS OF TREATMENT

Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds of the following general Formulas I, II and III are disclosed: STR1 Specifically the compounds are azabicyclo [2. 2.1] omimes, azabicyclo [2.2.2] oximes, azabicyclo [2.2.1] amines, azabicyclo [2.2.2] amines, azabicyclo [3.2.1] oximes and amine containing heterocyclic oximes wherein the heterocyclic ring contains from 4 to 5 [3 to 7] carbon atoms.