149981-18-0

Basic information

• Product Name: 3,7-dimethyl-8-phenylxanthine
• Synonyms: 3,7-dimethyl-8-phenylxanthine
• CAS NO: 149981-18-0
• Molecular Weight: 256.264
• Mol File: 149981-18-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3,7-dimethyl-8-phenylxanthine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,7-dimethyl-8-phenylxanthine(149981-18-0)
• EPA Substance Registry System: 3,7-dimethyl-8-phenylxanthine(149981-18-0)

Safety Data

• Hazardous Substances Data: 149981-18-0(Hazardous Substances Data)

Upstream product

• 38759-27-2 3,7-dimethyl-6-methylthio-2(3H)-purinone 
• 55441-70-8 6-amino-1-methyl-5-(methylamino)pyrimidine-2,4-dione 
• 14094-37-2 6-amino-5-bromo-1-methylpyrimidine-2,4(1H,3H)-dione 
• 2434-53-9 6-amino-1-methyluracil 
• 149981-38-4 6-amino-1-methyl-5-methyl(phenyl)carboxamido-2,3-dioxo-1,2,3,4-tetrahydropyrimidine 
• 155588-82-2 3,7-Dimethyl-6-methylsulfanyl-8-phenyl-3,7-dihydro-purin-2-one 
• 4921-55-5 8-chloro-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione 

Downstream Products

• 149981-23-7 1-allyl-3,7-dimethyl-8-phenylxanthine 
• 453591-29-2 6-((S)-1-Hydroxymethyl-propylamino)-3,7-dimethyl-8-phenyl-3,7-dihydro-purin-2-one 
• 453591-28-1 6-((R)-1-Hydroxymethyl-propylamino)-3,7-dimethyl-8-phenyl-3,7-dihydro-purin-2-one 
• 453591-27-0 6-(1-hydroxymethyl-propylamino)-3,7-dimethyl-8-phenyl-3,7-dihydro-purin-2-one 
• 453591-26-9 6-(2-hydroxy-ethylamino)-3,7-dimethyl-8-phenyl-3,7-dihydro-purin-2-one 
• 155588-82-2 3,7-Dimethyl-6-methylsulfanyl-8-phenyl-3,7-dihydro-purin-2-one 
• 6439-88-9 1,3,7-trimethyl-8-phenylxanthine 
• 453591-89-4 3,7-dimethyl-8-phenyl-6-thioxo-1,3,6,7-tetrahydro-purin-2-one 

Relevant articles and documents

Syntheses of 6- or 8-carbon-substituted 2-oxopurines

Reaction of 3,7-dimethyl-6-methylthio-2-oxopurine (1) with Grignard reagents or organolithiums afforded 8-adducts 2, whereas the corresponding reaction of 3,7-dimethyl-2-oxopurine (6) gave 6-adducts 7. The adducts 2 and 7 were converted into 8-substituted

Synthesis and structure-activity relationships of 3,7-dimethyl-1- propargylxanthine derivatives, A(2A)-selective adenosine receptor antagonists

A series of 8-substituted derivatives of 3,7-dimethyl-1- propargylxanthine (DMPX) was synthesized and investigated as A(2A) adenosine receptor antagonists. Different synthetic strategies for the preparation of DMPX derivatives and analogues were explored.