150074-77-4Relevant articles and documents
METHOD OF PREPARATION OF TERFENADINE AND ITS DERIVATIVES
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Page 9, (2010/02/07)
The invention relates to a new method of preparation of derivatives of piperidinyl butylphenylacetic acids. The compounds are histaminically active. The substances are prepared by Grignard reaction of alkylhalohydrins and suitably substituted aromatic aldehydes. The resulting diols are subjected to subsequent substitution reaction.