150193-49-0

Basic information

• Product Name: 2-{(2S,3S)-1-Benzyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2-methyl-malonic acid diallyl ester
• Synonyms: 2-{(2S,3S)-1-Benzyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2-methyl-malonic acid diallyl ester
• CAS NO: 150193-49-0
• Molecular Weight: 515.722
• Mol File: 150193-49-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{(2S,3S)-1-Benzyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2-methyl-malonic acid diallyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{(2S,3S)-1-Benzyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2-methyl-malonic acid diallyl ester(150193-49-0)
• EPA Substance Registry System: 2-{(2S,3S)-1-Benzyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2-methyl-malonic acid diallyl ester(150193-49-0)

Safety Data

• Hazardous Substances Data: 150193-49-0(Hazardous Substances Data)

Upstream product

• 150193-37-6 2-methylmalonic acid diallyl ester 
• 76899-07-5 (3R,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-acetoxyazetidin-2-one 
• 100-39-0 benzyl bromide 
• 150193-38-7 (3S,4S)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-[1,1-di(allyloxycarbonyl)ethyl]-2-azetidinone 

Relevant articles and documents

A Simple and Highly Diastereoselective Synthesis of A 1β-Methylcarbapenem Key Intermediate by Deallyloxycarbonylation Using Palladium Complexes

A simple, highly diastereoselective synthesis of the key 1β-methylcarbapenem intermediate 1 has been accomplished via a palladium catalyzed deallyloxycarbonylation of diallyl malonate derivative 4a which was readily prepared from (3S,4R)-4-acetoxy-3--2-azetidinone 2 in two steps.