15024-11-0

Basic information

• Product Name: 4-methylphenyl 4-nitrobenzoate
• Synonyms: 4-Nitro-benzoic acid p-tolyl ester
• CAS NO: 15024-11-0
• Molecular Formula: C₁₄H₁₁NO₄
• Molecular Weight: 257.2414
• Mol File: 15024-11-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 409.7°C at 760 mmHg
• Flash Point: 181.9°C
• Density: 1.28g/cm³
• Vapor Pressure: 6.37E-07mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: 4-methylphenyl 4-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methylphenyl 4-nitrobenzoate(15024-11-0)
• EPA Substance Registry System: 4-methylphenyl 4-nitrobenzoate(15024-11-0)

Safety Data

• Hazardous Substances Data: 15024-11-0(Hazardous Substances Data)

Upstream product

• 106-44-5 p-cresol 
• 636-98-6 p-nitrobenzene iodide 
• 201230-82-2 carbon monoxide 
• 1121-70-6 sodium 4-methylphenoxide 
• 122-04-3 4-nitro-benzoyl chloride 
• 62-23-7 4-nitro-benzoic acid 
• 100-66-3 methoxybenzene 
• 555-16-8 4-nitrobenzaldehdye 
• 619-80-7 4-nitrobenzamide 

Downstream Products

• 106-44-5 p-cresol 
• 64026-23-9 N-dodecyl-p-nitrobenzamide 
• 62-23-7 4-nitro-benzoic acid 
• 943-39-5 4-nitroperbenzoic acid 

Relevant articles and documents

Br?nsted Acid Mediated Nucleophilic Functionalization of Amides through Stable Amide C?N Bond Cleavage; One-Step Synthesis of 2-Substituted Benzothiazoles

We have developed a Br?nsted acid mediated synthetic method to directly cleave stable amide C?N bonds by a variety of alcohol and amine nucleophiles. Reverse reactivity was observed and alcoholysis of amides by activated primary and secondary benzylic, and propargylic alcohols have been achieved instead of the expected nucleophilic substitution of alcohols. As an application, 2-substituted benzothiazole derivatives have been synthesized in one pot employing 2-aminothiophenol as nucleophile.

Sodium cyanide-promoted copper-catalysed aerobic oxidative synthesis of esters from aldehydes

A simple and efficient copper-catalysed procedure for oxidative esterification of aldehydes with alcohols and phenols mediated by sodium cyanide, using air as a clean oxidant, is described. A variety of aromatic aldehydes and structurally different alcohols and phenols reacted efficiently, and the product esters were obtained in good to excellent yields under normal atmospheric and solvent-free conditions.

A microwave-assisted highly practical chemoselective esterification and amidation of carboxylic acids

The ubiquitousness of esters and amide functionalities makes their coupling reaction one of the most sought-after organic transformations. Herein, we have described an efficient microwave-assisted synthesis of esters and amides. Soluble triphenylphosphine, in conjugation with molecular iodine, gave the desired products without the requirement for a base/catalyst. In addition, a solid-phase synthetic route is incorporated for the said conversion, which has added advantages over solution-phase pathways, such as low moisture sensitivity, easy handling, isolation of the product by simple filtration, and reusability. In short, our method is simple, mild, green, and highly chemoselective in nature.