15034-21-6

Basic information

• Product Name: Quinoxaline, 2-methyl-3-phenyl-, 1,4-dioxide
• CAS NO: 15034-21-6
• Molecular Formula: C15H12N2O2
• Molecular Weight: 252.272
• Mol File: 15034-21-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Quinoxaline, 2-methyl-3-phenyl-, 1,4-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoxaline, 2-methyl-3-phenyl-, 1,4-dioxide(15034-21-6)
• EPA Substance Registry System: Quinoxaline, 2-methyl-3-phenyl-, 1,4-dioxide(15034-21-6)

Safety Data

• Hazardous Substances Data: 15034-21-6(Hazardous Substances Data)

Upstream product

• 100-58-3 phenylmagnesium bromide 
• 39576-78-8 2-chloro-3-methylquinoxaline 1,4-dioxide 
• 1402051-60-8 2-(benzylsulfanyl)-3-methylquinoxaline 1,4-dioxide 
• 98-80-6 phenylboronic acid 
• 480-96-6 benzofurazan oxide 
• 88-74-4 2-nitro-aniline 
• 103-79-7 1-phenyl-acetone 
• 93-55-0 1-phenyl-propan-1-one 
• 79-21-0 peracetic acid 
• 10130-23-1 2-methyl-3-phenylquinoxaline 

Downstream Products

• 10130-23-1 2-methyl-3-phenylquinoxaline 

Relevant articles and documents

Near room temperature cross-coupling reactions of arene boronic acids with a quinoxaline 1,4-dioxide benzylsulfanyl derivative

A new quinoxaline 1,4-dioxide benzylsulfanyl derivative was tested under mild conditions in copper-mediated Liebeskind-Srogl (LS) cross-coupling reactions with arene boronic acids. These first organometallic cross-coupling reactions performed on a quinoxaline 1,4-dioxide derivative open new perspectives in medicinal chemistry. They represent also the first LS cross-couplings run with an electrophile equipped with an aryl N-oxide moiety. A mild an efficient protocol was developed to prepare quinoxaline 1,4-dioxide derivatives. A benzylsulfanyl quinoxaline 1,4-dioxide derivative was engaged as an electrophilic partner in copper-mediated Liebeskind-Srogl cross-coupling reactions with a wide range of arene boronic acids. These experiments represent the first organometallic coupling reactions on quinoxaline 1,4-dioxide derivatives. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Cosmetic composition for imparting to human skin a coloration resembling a natural tan

A cosmetic composition for imparting to human skin after exposure to sunlight a coloration resembling a natural tan comprises a cosmetic vehicle suitable for topical application to the skin and an effective amount of at least one compound of the formula STR1 wherein R1 and R2 each independently represent hydrogen, an aliphatic radical having 1-18 carbon atoms, carbalkoxy having 2-5 carbon atoms, acyl having 2-5 carbon atoms, aryl, aryl substituted by alkyl having 1-4 carbon atoms or hydroxy, a heterocycle containing 4-6 members, substituted or not by alkyl having 1-4 carbon atoms, halogen or hydroxy, or R1 and R2 together form a saturated ring containing 4-12 chains, optionally substituted by alkyl having 1-4 carbon atoms, halogen or hydroxy, or bridged and containing a heteroatom selected from N, O or S; and R3 represents hydrogen, a lower aliphatic group containing 1-6 carbon atoms, lower alkoxy containing 1-4 carbon atoms or halogen, with the proviso that R1, R2 and R3 are not hydrogen simultaneously; and an acid addition salt thereof.