150347-58-3

Basic information

• Product Name: 5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER
• Synonyms: SPIRO[7H-DIBENZO[C,H]XANTHENE-7,1'(3'H)-ISOBENZOFURAN], 2,5-PYRROLIDINEDIONE;5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER;5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUC-CIN;5-(6)-Carboxynaphthofluoroscein N-succinimidyl ester;2,5-Pyrrolidinedione, 1-[[[3,11-dihydroxy-3'-oxospiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-5'(or6')-yl]carbonyl]oxy]-;1-[[[3,11-Dihydroxy-3'-oxospiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-5'(or 6')-yl]carbonyl]oxy]-2,5-pyrrolidinedione;3,11-Dihydroxy-3'-oxospiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]carboxylic acid 2,5-dioxo-1-pyrrolidinyl ester;CNF,SE [5(6)-Carboxynaphthofluorescein , succiniMidyl ester]
• CAS NO: 150347-58-3
• Molecular Formula: C33H19NO9
• Molecular Weight: 573.51
• Mol File: 150347-58-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• Solubility: DMSO: soluble
• CAS DataBase Reference: 5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER(150347-58-3)
• EPA Substance Registry System: 5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER(150347-58-3)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 8-10-21
• Hazardous Substances Data: 150347-58-3(Hazardous Substances Data)

Usage

Description

5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER, also known as 5-(6)-Carboxynaphthofluoroscein N-Succinimidyl Ester, is a derivative compound of 5(6)-Carboxyfluorescein (C178315). It is an amine-reactive fluorescent probe used for the conjugation of peptides or proteins. 5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER is characterized by its ability to form hydrolytically stable fluorescent conjugates, making it a valuable reagent in various applications.

Uses

Used in Biochemical Research:
5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER is used as a fluorescent probe for the conjugation of peptides or proteins. This application is particularly useful in biochemical research, as it allows for the tracking and analysis of specific biomolecules within complex biological systems.
Used in the Synthesis of Fluorescent Reagents:
As a derivative of 5(6)-Carboxyfluorescein, 5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER serves as a useful starting material for the synthesis of other fluorescein-derived reagents. These synthesized reagents can be employed in a variety of applications, including the development of new fluorescent probes and the enhancement of existing ones.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER is used as a key component in the development of drug delivery systems. Its ability to form stable conjugates with peptides and proteins makes it an ideal candidate for targeted drug delivery, potentially improving the efficacy and specificity of therapeutic agents.
Used in Diagnostic Applications:
The amine-reactivity and fluorescence properties of 5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER make it a valuable tool in the development of diagnostic assays. By conjugating this compound with specific biomolecules, researchers can create highly sensitive and selective diagnostic tools for the detection and monitoring of various diseases and conditions.
Used in Environmental Monitoring:
5(6)-CARBOXYNAPHTHOFLUORESCEIN N-SUCCINIMIDYL ESTER can also be employed in environmental monitoring applications. By conjugating this compound with environmentally relevant molecules, it is possible to develop sensors and assays for the detection and quantification of pollutants, contaminants, and other substances of concern in the environment.