150403-88-6

Basic information

• Product Name: L-N5-(1-IMINOETHYL)ORNITHINE*HYDROCHLORI DE
• Synonyms: L-NIO hydrochloride, L-Ornithine ω-acetamidine hydrochloride;Nδ-(IMinoethyl)-L-ornithine;L-Ornithine ψ-acetamidine hydrochloride;N(5)-(1-Iminoethyl)-L-ornithine HCl (L-NIO);(S)-5-Acetimidamido-2-aminopentanoic acid hydrochloride
• CAS NO: 150403-88-6
• Molecular Formula: C7H15N3O2.ClH
• Molecular Weight: 209.675
• Product Categories: Amino Acids & Derivatives;Nitric Oxide Reagents;Amino Acids & Derivatives, Nitric Oxide Reagents
• Mol File: 150403-88-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 225-226°C
• Boiling Point: 358.9°Cat760mmHg
• Flash Point: 170.9°C
• Appearance: white to beige/
• Density: g/cm³
• Vapor Pressure: 4E-06mmHg at 25°C
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: H2O: soluble2mg/mL, clear (warmed)
• Stability: Hygroscopic
• CAS DataBase Reference: L-N5-(1-IMINOETHYL)ORNITHINE*HYDROCHLORI DE(CAS DataBase Reference)
• NIST Chemistry Reference: L-N5-(1-IMINOETHYL)ORNITHINE*HYDROCHLORI DE(150403-88-6)
• EPA Substance Registry System: L-N5-(1-IMINOETHYL)ORNITHINE*HYDROCHLORI DE(150403-88-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 150403-88-6(Hazardous Substances Data)

Usage

Description

L-N5-(1-IMINOETHYL)ORNITHINEHYDROCHLORI DE, also known as L-N5-(1-Iminomethyl)ornithine hydrochloride, is a chemical compound with the molecular formula C6H15N3O2HCl. It is a white to off-white solid and is recognized for its potent and reversible inhibitory effects on nitric oxide (NO) synthase in various tissues, including adrenal glands, brain, and vascular endothelial cells.

Uses

Used in Pharmaceutical Industry:
L-N5-(1-IMINOETHYL)ORNITHINEHYDROCHLORI DE is used as a pharmaceutical compound for its ability to inhibit nitric oxide synthase. This inhibition can be beneficial in the development of treatments for conditions where excessive nitric oxide production is a concern, such as certain inflammatory diseases, neurological disorders, and cardiovascular conditions.
Used in Research Applications:
In the field of scientific research, L-N5-(1-IMINOETHYL)ORNITHINEHYDROCHLORI DE serves as a valuable tool for studying the role of nitric oxide synthase in various biological processes. By inhibiting the enzyme, researchers can gain insights into the mechanisms underlying nitric oxide-related pathways and identify potential therapeutic targets for future drug development.
Used in Drug Development:
L-N5-(1-IMINOETHYL)ORNITHINEHYDROCHLORI DE is also utilized in the development of new drugs targeting nitric oxide synthase. Its potent and reversible inhibition properties make it a promising candidate for the creation of medications aimed at treating diseases associated with dysregulated nitric oxide production.

InChI:InChI=1/C7H15N3O2.ClH/c1-5(8)10-4-2-3-6(9)7(11)12;/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12);1H/t6-;/m0./s1