15043-03-5

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 6-ethyl- (9CI)
• Synonyms: 2,4(1H,3H)-Pyrimidinedione, 6-ethyl- (9CI);6-Ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione;2,4(1H,3H)-PyriMidinedione, 6-ethyl-;6-ethyl-2,4(1H,3H)-Pyrimidinedione;6-ethylpyrimidine-2,4-diol
• CAS NO: 15043-03-5
• Molecular Formula: C6H8N2O2
• Molecular Weight: 140.13992
• Product Categories: PYRIMIDINE
• Mol File: 15043-03-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 411.7°Cat760mmHg
• Flash Point: 202.8°C
• Appearance: /
• Density: 1.164g/cm³
• Vapor Pressure: 2.29E-07mmHg at 25°C
• Refractive Index: 1.482
• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 6-ethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 6-ethyl- (9CI)(15043-03-5)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 6-ethyl- (9CI)(15043-03-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 15043-03-5(Hazardous Substances Data)

Usage

General Description

2,4(1H,3H)-Pyrimidinedione, 6-ethyl- (9CI) is a chemical compound with the molecular formula C6H8N2O2. Also known as 6-ethyluracil, it is a derivative of uracil and belongs to the pyrimidine family of compounds. It is a white crystalline solid with a melting point of 219-221°C and is soluble in hot water and ethanol. 6-ethyluracil is used in the synthesis of pharmaceuticals and agrochemicals, and it also has potential applications in the field of organic chemistry and biochemical research. 2,4(1H,3H)-Pyrimidinedione, 6-ethyl- (9CI) has been studied for its antiviral and antitumor properties, and it is also used as an intermediate in the synthesis of various bioactive molecules.

InChI:InChI=1/C6H8N2O2/c1-2-4-3-5(9)8-6(10)7-4/h3H,2H2,1H3,(H2,7,8,9,10)

Upstream product

• 53939-83-6 6-ethyl-2,3-dihydro-2-thioxopyrimidin-4(1H)-one 
• 5734-66-7 6-ethylisocytosine 
• 82830-93-1 6-ethyl-2-methoxy-4(3H)-pyrimidinone 
• 4949-44-4 ethyl propanoylacetate 
• 57-13-6 urea 
• 6554-65-0 2,4-dichloro-6-ethylpyrimidine 

Downstream Products

• 178425-34-8 1-[(2S,4S,5S)-4-Azido-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-6-ethyl-1H-pyrimidine-2,4-dione 
• 178425-35-9 1-[(2R,4S,5S)-4-Azido-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-6-ethyl-1H-pyrimidine-2,4-dione 
• 147909-83-9 6-Ethyl-1-(2,3,5-tri-O-benzoyl-α-D-arabinofuranosyl)uracil 
• 141602-25-7 4-chloro-6-ethylpyrimidine 
• 856160-67-3 6-ethylpyrimidin-4-amine 
• 102170-34-3 6-ethyl-pyrimidine-2,4,5-triyltriamine 
• 1373331-51-1 1-(7-chloro-5-ethyl-1-phenyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-yl)-2-phenyldiazene 

Relevant articles and documents

DIHYDROPTERIDINONES I

The present invention relates to dihydropteridinones, their use as modulators of γ-secretase and to pharmaceutical compositions containing said compounds. In particular, the present invention relates to compounds which interfere with γ-secretase and/or it

DIHYDROPTERIDINONES I

The present invention relates to dihydropteridinones, their use as modulators of γ-secretase and to pharmaceutical compositions containing said compounds. In particular, the present invention relates to compounds which interfere with γ-secretase and/or it

Synthesis of modified uracil and cytosine nucleobases using a microwave-assisted method

Modified nucleobases and nucleic acids have found many biological and pharmaceutical applications. Here we report a microwave-directed synthesis of a variety of modified uracil and cytosine nucleobases with high yields under solvent-free conditions. The reaction yields were further improved by addition of Lewis acid. The crystal structures of 5-isopropyl-6-methyluracil and 6-phenyluracil were also determined.