150587-07-8 Usage
Description
21-BENZYLOXY-9-ALPHA-FLUORO-11-BETA,17-ALPHA-DIHYDROXY-16-ALPHA-METHYLPREGNA-1,4-DIENE-3,20-DIONE, also known as Dexamethasone Beloxil, is a corticosteroid with potent anti-inflammatory properties. It is a synthetic derivative of the naturally occurring hormone cortisol, modified to enhance its anti-inflammatory and immunosuppressive effects. 21-BENZYLOXY-9-ALPHA-FLUORO-11-BETA,17-ALPHA-DIHYDROXY-16-ALPHA-METHYLPREGNA-1,4-DIENE-3,20-DIONE is characterized by its benzyloxy group at the 21st position, a fluorine atom at the 9th position, and hydroxyl groups at the 11th and 17th positions, along with a methyl group at the 16th position. Its structural features contribute to its effectiveness in treating various inflammation-related conditions.
Uses
Used in Ophthalmology:
Dexamethasone Beloxil is used as an anti-inflammatory agent for the treatment of various eye conditions, including uveitis, iritis, keratitis, postsurgical inflammation, vernal keratoconjunctivitis, and giant papillary conjunctivitis. Its potent anti-inflammatory action helps to reduce swelling, redness, itching, and pain associated with these conditions, promoting faster recovery and improved visual outcomes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Dexamethasone Beloxil is utilized as an active pharmaceutical ingredient in the development of medications targeting inflammation and immune response modulation. Its synthesis and formulation into various dosage forms, such as eye drops, injections, or oral medications, allow for targeted delivery and effective management of inflammation-related disorders.
Used in Research and Development:
Dexamethasone Beloxil is also used in research and development for studying the mechanisms of inflammation, immune response, and the effects of corticosteroids on various cell types and signaling pathways. This knowledge contributes to the advancement of novel therapeutic strategies and the development of new anti-inflammatory drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 150587-07-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,5,8 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 150587-07:
(8*1)+(7*5)+(6*0)+(5*5)+(4*8)+(3*7)+(2*0)+(1*7)=128
128 % 10 = 8
So 150587-07-8 is a valid CAS Registry Number.
InChI:InChI=1/C29H35FO5/c1-18-13-23-22-10-9-20-14-21(31)11-12-26(20,2)28(22,30)24(32)15-27(23,3)29(18,34)25(33)17-35-16-19-7-5-4-6-8-19/h4-8,11-12,14,18,22-24,32,34H,9-10,13,15-17H2,1-3H3/t18-,22+,23+,24+,26+,27+,28+,29+/m1/s1
150587-07-8Relevant articles and documents
Anti-inflammatory compounds for ophthalmic use
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, (2008/06/13)
Anti-inflammatory compounds, a method of treating inflamed ocular tissue and compositions of these compounds are described. The compounds are derivatives and analogues of known steroid compounds (e.g., dexamethasone) and are advantageously characterized i
