15070-84-5

Basic information

• Product Name: 5-AMINO-1-(3-CHLORO-PHENYL)-1 H-PYRAZOLE-4-CARBOXYLIC ACID
• Synonyms: BUTTPARK 20\09-26;5-AMINO-1-(3-CHLORO-PHENYL)-1 H-PYRAZOLE-4-CARBOXYLIC ACID;5-AMINO-1-(3-CHLOROPHENYL)PYRAZOLE-4-CARBOXYLIC ACID;TIMTEC-BB SBB006937;SALOR-INT L252050-1EA
• CAS NO: 15070-84-5
• Molecular Formula: C₁₀H₈ClN₃O₂
• Molecular Weight: 237.64
• Mol File: 15070-84-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-AMINO-1-(3-CHLORO-PHENYL)-1 H-PYRAZOLE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-1-(3-CHLORO-PHENYL)-1 H-PYRAZOLE-4-CARBOXYLIC ACID(15070-84-5)
• EPA Substance Registry System: 5-AMINO-1-(3-CHLORO-PHENYL)-1 H-PYRAZOLE-4-CARBOXYLIC ACID(15070-84-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 15070-84-5(Hazardous Substances Data)

Usage

General Description

5-AMINO-1-(3-CHLORO-PHENYL)-1 H-PYRAZOLE-4-CARBOXYLIC ACID is a chemical compound with a pyrazole structure. It consists of a pyrazole ring with an amino group at the 5-position and a carboxylic acid group at the 4-position, as well as a 3-chloro-phenyl substituent. 5-AMINO-1-(3-CHLORO-PHENYL)-1 H-PYRAZOLE-4-CARBOXYLIC ACID has potential applications in pharmaceutical research and drug development, as pyrazole derivatives have been found to exhibit various biological activities, including antimicrobial, antitumor, and antiviral properties. The presence of the carboxylic acid group also makes it a useful building block for the synthesis of more complex organic compounds.

Upstream product

• 15001-08-8 5-amino-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylic acid,ethyl ester 
• 2312-23-4 m-chlorophenylhydrazine hydrochloride 

Relevant articles and documents

Synthesis of pyrazole-carboxamides and pyrazole-carboxylic acids derivatives: Simple methods to access powerful building blocks

Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.

NOVEL MACROCYCLES AS FACTOR XIA INHIBITORS

The present invention provides compounds of Formula (Ia): or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.