150767-07-0Relevant articles and documents
Facile Synthesis of Potent HIV-1 Protease Inhibitors containing a Novel Pseudo-symmetric Dipeptide Isostere
Sham, Hing L.,Betebenner, David A.,Zhao, Chen,Wideburg, Norman E.,Saldivar, Ayda,et al.
, p. 1052 - 1053 (2007/10/02)
A series of potent inhibitors of the HIV-1 protease containing a novel pseudo-symmetric dipeptide isostere 3 was synthesized via ring opening of a protected epoxide with various substituted hydrazines.