150807-21-9Relevant articles and documents
Design, synthesis, and biological evaluation of novel cRGD-paclitaxel conjugates for integrin-assisted drug delivery
Pilkington-Miksa, Michael,Arosio, Daniela,Battistini, Lucia,Belvisi, Laura,De Matteo, Marilenia,Vasile, Francesca,Burreddu, Paola,Carta, Paola,Rassu, Gloria,Perego, Paola,Carenini, Nives,Zunino, Franco,De Cesare, Michelandrea,Castiglioni, Vittoria,Scanziani, Eugenio,Scolastico, Carlo,Casiraghi, Giovanni,Zanardi, Franca,Manzoni, Leonardo
experimental part, p. 1610 - 1622 (2012/10/08)
The efficacy of taxane-based antitumor therapy is limited by several drawbacks which result in a poor therapeutic index. Thus, the development of approaches that favor selective delivery of taxane drugs (e.g., paclitaxel, PTX) to the disease area represen