15093-43-3 Usage
General Description
N-Phenyl-N'-(3-phenylpropyl)thiourea is a chemical compound with the molecular formula C16H18N2S. It is a thiourea derivative that is primarily used as a rubber accelerator in the production of tires and other rubber products. N-Phenyl-N'-(3-phenylpropyl)thiourea is also used as a catalyst in the synthesis of organic compounds and as a stabilizer in the production of plastics. N-Phenyl-N'-(3-phenylpropyl)thiourea is a white crystalline solid that is relatively stable under normal conditions, but it should be handled with care due to its irritant and toxic properties. It is important to follow proper safety precautions when handling this compound to avoid any potential health hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 15093-43-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,0,9 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 15093-43:
(7*1)+(6*5)+(5*0)+(4*9)+(3*3)+(2*4)+(1*3)=93
93 % 10 = 3
So 15093-43-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H18N2S/c19-16(18-15-11-5-2-6-12-15)17-13-7-10-14-8-3-1-4-9-14/h1-6,8-9,11-12H,7,10,13H2,(H2,17,18,19)
15093-43-3Relevant articles and documents
Structural requirement of phenylthiourea analogs for their inhibitory activity of melanogenesis and tyrosinase
Thanigaimalai, Pillaiyar,Lee, Ki-Cheul,Sharma, Vinay K.,Joo, Cheonik,Cho, Won-Jea,Roh, Eunmiri,Kim, Youngsoo,Jung, Sang-Hun
experimental part, p. 6824 - 6828 (2011/12/22)
Effect of a series of 1-phenylthioureas 1a-k and 1,3-disubstituted thioureas 2a-k were evaluated against melanin formation in melanoma B16 cell line and mushroom tyrosinase. Inhibitory activity of tyrosinase of 1-phenylthioureas 1a-k is parallel to their melanogenic inhibition. Thus, the melanogenic inhibition in melanoma B16 cells of 1-phenylthioureas could be the result of inhibition of tyrosinase. However, 1,3-diaryl or 1-phenyl-3- alkylthioureas, 2a-k, appears as melanogenic inhibitor without inhibition of tyrosinase. The molecular docking study of 1e and 2b to binding pocket of tyrosinase provided convincing explanation regarding the necessity of direct connection of planar phenyl to thiourea unit without N′-substitution of phenylthioureas 1 as tyrosinase inhibitor and 2 as non-tyrosinase inhibitor.
