151094-81-4 Usage
Description
(2S)-2-(2,4-dioxo-1H-quinazolin-3-yl)-3-phenyl-propanoic acid is a chiral molecule with the molecular formula C21H14N2O5. It is a derivative of quinazolin-4(3H)-one, containing a phenyl and a propanoic acid group. (2S)-2-(2,4-dioxo-1H-quinazolin-3-yl)-3-phenyl-propanoic acid has a stereocenter at the second carbon atom, which contributes to its unique properties. Its structure suggests potential pharmaceutical applications and may exhibit biological activities such as anti-inflammatory, antibacterial, or antifungal properties. However, the exact uses and properties of this chemical have not been fully characterized or documented, indicating a need for further study and development in the pharmaceutical and medicinal fields.
Uses
Used in Pharmaceutical Industry:
(2S)-2-(2,4-dioxo-1H-quinazolin-3-yl)-3-phenyl-propanoic acid is used as a potential pharmaceutical candidate for various applications due to its unique structure and chiral nature. Its potential biological activities, such as anti-inflammatory, antibacterial, or antifungal properties, make it a promising compound for the development of new drugs and therapies.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (2S)-2-(2,4-dioxo-1H-quinazolin-3-yl)-3-phenyl-propanoic acid serves as a valuable compound for further study and development. Its structure and potential biological activities provide a foundation for exploring its interactions with biological targets and understanding its mechanisms of action. This knowledge can contribute to the design and synthesis of more effective and targeted pharmaceutical agents.
Check Digit Verification of cas no
The CAS Registry Mumber 151094-81-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,0,9 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 151094-81:
(8*1)+(7*5)+(6*1)+(5*0)+(4*9)+(3*4)+(2*8)+(1*1)=114
114 % 10 = 4
So 151094-81-4 is a valid CAS Registry Number.
151094-81-4Relevant articles and documents
A general and efficient solid phase synthesis of quinazoline-2,4-diones
Gordeev, Mikhail F.,Hui, Hon C.,Gordon, Eric M.,Patel, Dinesh V.
, p. 1729 - 1732 (1997)
An efficient solid phase synthesis of chiral quinazolinediones is described. Immobilized amino acid based urea derivatives 3 undergo a racemization-free heterocyclization upon gentle healing in presence of tetramethylguanidine to afford fused pyrimidine-2,4-diones 6, which are smoothly N1-alkylated under mild conditions to produce immobilized quinazolinediones 8. The method is amenable to combinatorial synthesis and offers broad scope for structural and chemical diversity, as illustrated by preparation of fused thieno[2,3-d]pyrimidine-2,4-dione 10 and hydroxamate pharmacophore bearing quinazolinedione derivative 11.
Solid phase synthesis of chiral 3-substituted quinazoline-2,4-diones
Gouilleux, Laurent,Fehrentz, Jean-Alain,Winternitz,Martinez, Jean
, p. 7031 - 7034 (2007/10/03)
The synthesis of chiral 3-substituted quinazoline-2,4-diones was performed starting from N-urethane anthranilamides. This synthetic pathway was applied in solid phase, from commercially available anthranilic acid that was bound to hydroxymethyl polystyrene resin via a carbamate linker. In both cases, cyclisation occurred under basic conditions to afford non-racemized quinazolinediones in high purity.
