151160-05-3

Basic information

• Product Name: 2-Propenal, 3-iodo-, (2E)-
• Synonyms: (E)-3-Iodoprop-2-enal;(E)-3-Iodopropenal;(E)-iodoacrolein;3-iodoacrolein;(E)-3-Iodo-propenal;(2E)-3-iodopropenal
• CAS NO: 151160-05-3
• Molecular Formula: C3H3IO
• Molecular Weight: 181.96000
• Mol File: 151160-05-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propenal, 3-iodo-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenal, 3-iodo-, (2E)-(151160-05-3)
• EPA Substance Registry System: 2-Propenal, 3-iodo-, (2E)-(151160-05-3)

Safety Data

• Hazardous Substances Data: 151160-05-3(Hazardous Substances Data)

Upstream product

• 31930-36-6 ethyl (E)-3-iodopropenoate 
• 1730-25-2 allylmagnesium bromide 

Downstream Products

• 270918-58-6 (E)-5-(Phenylthio)pent-2-en-4-inal 
• 270918-57-5 (E)-5-Phenoxypent-2-en-4-inal 
• 168106-72-7 (E)-5-(N-Methylanilino)pent-2-en-4-inal 
• 168106-69-2 (E)-5-Dimethylamino-pent-2-en-4-ynal 

Relevant articles and documents

Flow synthesis of (3R)- and (3S)-(E)-1-iodohexa-1,5-dien-3-ol: Chiral building blocks for natural product synthesis

A concise procedure to prepare optically active (3R)- and (3S)-(E)-1-iodohexa-1,5-dien-3-ol was developed. Ethyl (E)-3-iodoacrylate was converted to racemic (E)-1-iodohexa-1,5-dien-3-ol under flow and batch conditions via successive half reduction followed by Grignard reaction. Kinetic resolution of the racemic alcohol was achieved under flow conditions by using lipase packed in a column to afford (3S)-(E)-1-iodohexa-1,5-dien-3-ol and corresponding (3R)-acetate. Removal of the acetyl group was also carried out under flow conditions by using ion exchange resin packed in a column and (3R)-(E)-1-iodohexa-1,5-dien-3-ol was obtained after simple evaporation of the eluent.