151206-37-0Relevant articles and documents
Asymmetric Photocatalytic C(sp3)-H Bond Addition to α-Substituted Acrylates
Dai, Zhen-Yao,Nong, Zhong-Sheng,Song, Shun,Wang, Pu-Sheng
supporting information, p. 3157 - 3161 (2021/05/05)
Asymmetric functionalization of inert C(sp3)-H bonds is a straightforward approach to realize versatile bond-forming events, allowing the precise assembly of molecular complexity with minimal functional manipulations. Here, we describe an asymmetric photocatalytic C(sp3)-H bond addition to α-substituted acrylates by using tetrabutylammonium decatungstate (TBADT) as a hydrogen atom transfer (HAT) photocatalyst and chiral phosphoric acid as a chiral proton-transfer shuttle. This protocol is supposed to occur via a radical/ionic relay process, including a TBADT-mediated HAT to cleave the inert C(sp3)-H bond, a 1,4-radical addition, a back hydrogen abstraction, and an enantioselective protonation. A variety of inert C-H bond patterns and α-substituted acrylates are well tolerated to enable the rapid synthesis of enantioenriched α-stereogenic esters from simple raw materials.
Markovnikov-Selective Palladium Catalyst for Carbonylation of Alkynes with Heteroarenes
Liu, Jie,Li, Haoquan,Dühren, Ricarda,Liu, Jiawang,Spannenberg, Anke,Franke, Robert,Jackstell, Ralf,Beller, Matthias
supporting information, p. 11976 - 11980 (2017/09/06)
A new class of palladium catalysts, based on heterocyclic diphosphines, was rationally designed and synthesized. Application of one of these catalysts allows novel Markovnikov-selective carbonylation of non-activated alkynes with heteroarenes to give the
Rh(I)-catalyzed cross-coupling of α-diazoesters with arylsiloxanes
Xia, Ying,Liu, Zhen,Feng, Sheng,Ye, Fei,Zhang, Yan,Wang, Jianbo
supporting information, p. 956 - 959 (2015/03/30)
An Rh(I)-catalyzed cross-coupling of diazoesters with arylsiloxanes has been successfully achieved. This transformation is a new method for the construction of the C(sp3)-C(sp2) bond, thus providing an alternative synthesis of α-aryl esters. Rh(I)-carbene migratory insertion has been proposed to be involved in this coupling reaction. The reaction represents the first example of utilizing arylsiloxane as the coupling partner in the carbene-involved cross-coupling reactions.
