151489-85-9 Usage
Description
(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine, also known as (S)-(+)-1,1'-Bi(2-naphthol), is a chiral diamine compound that plays a significant role in the synthesis of chiral ligands and catalysts. It is widely used in asymmetric catalysis for the enantioselective synthesis of various organic compounds. (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine is a key building block in the production of pharmaceuticals, agrochemicals, and materials. Its unique structure, featuring two methoxy groups attached to the biphenyl core, along with its chiral nature, makes it a valuable chemical for controlling the stereochemistry of reactions in organic synthesis. Overall, (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine is a versatile and important compound in the field of asymmetric synthesis and catalysis.
Uses
Used in Pharmaceutical Industry:
(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine is used as a key intermediate for the synthesis of various pharmaceuticals. Its chiral nature allows for the production of enantiomerically pure compounds, which is crucial for the development of effective and safe medications.
Used in Agrochemical Industry:
In the agrochemical industry, (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine is utilized as a precursor for the synthesis of chiral agrochemicals. Its ability to control stereochemistry in reactions contributes to the development of more effective and targeted pesticides and other agricultural products.
Used in Materials Science:
(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine is employed as a building block for the development of new materials with specific properties. Its chiral structure and functional groups enable the creation of materials with unique characteristics, such as chiral polymers and other advanced materials.
Used in Asymmetric Catalysis:
As a chiral diamine compound, (1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine is used as a ligand or catalyst in asymmetric catalysis. It plays a crucial role in the enantioselective synthesis of various organic compounds, enabling the production of enantiomerically pure products with high selectivity and efficiency.
Used in Research and Development:
(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diamine is also used in research and development for the exploration of new synthetic methods, catalysts, and ligands. Its unique properties and reactivity make it an attractive candidate for studying and developing innovative approaches in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 151489-85-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,4,8 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 151489-85:
(8*1)+(7*5)+(6*1)+(5*4)+(4*8)+(3*9)+(2*8)+(1*5)=149
149 % 10 = 9
So 151489-85-9 is a valid CAS Registry Number.
151489-85-9Relevant articles and documents
Synthetic method for optically pure double-helix oligomeric tetra-benzocyclooctene substances
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, (2017/07/31)
The invention discloses a synthetic method for optically pure double-helix oligomeric tetra-benzocyclooctene substances. The synthetic method comprises the following steps: (1) carrying out oxidative cross-coupling on diiodo dimethoxy biphenyl (51) and 2,2',6,6'-biphenyl tetrabromide (97) to obtain 1,16-dibromo-8,9-dimethoxy tetra-benzocyclooctene (96); (2) splitting the compound (96), thus obtaining optically pure (S, S)-96 and (R, R)-96; (3) taking the compound (96) as a raw material, synthesizing an intermediate (116) containing 6 benzene rings; (4) splitting the intermediate (116) to obtain (M)-116 and (P)-116; (5) making the optically pure (S, S)-96 and (M)-116 reacted to obtain target products, namely (M) -117, (M)-149 and (M)-150; and/or: making the (R, R)-96 and (P)-116 reacted to obtain target products, namely (P)-117, (P)-149 and (P)-150.
Chiral biphenylamide derivative: An efficient organocatalyst for the enantioselective synthesis of α-hydroxy phosphonates
Jiang, Jun,Chen, Xiaohong,Wang, Jun,Hui, Yonghai,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
supporting information; experimental part, p. 4355 - 4357 (2009/12/25)
The aldol reactions of α-keto phosphonates and aldehydes were facilitated by an axially chiral biphenylprolinamide under mild conditions, affording the synthetically and pharmaceutically useful products in high yields and excellent enantioselectivities.
