1516898-88-6

Basic information

• Product Name: 1-ethyl-2-phenyl-3-((trifluoromethyl)thio)-1H-indole
• Synonyms: 1-ethyl-2-phenyl-3-((trifluoromethyl)thio)-1H-indole
• CAS NO: 1516898-88-6
• Molecular Weight: 321.366
• Mol File: 1516898-88-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-ethyl-2-phenyl-3-((trifluoromethyl)thio)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethyl-2-phenyl-3-((trifluoromethyl)thio)-1H-indole(1516898-88-6)
• EPA Substance Registry System: 1-ethyl-2-phenyl-3-((trifluoromethyl)thio)-1H-indole(1516898-88-6)

Safety Data

• Hazardous Substances Data: 1516898-88-6(Hazardous Substances Data)

Upstream product

• 1516899-04-9 N,N-diethyl-2-(phenylethynyl)aniline 
• 1045821-71-3 N-[(trifluoromethyl)sulfanyl]aniline 
• 13228-39-2 1-ethyl-2-phenyl-1H-indole 
• 2926-29-6 Langlois reagent 

Relevant articles and documents

Transition-metal- and phosphorus-free electrophilic trifluoromethylthiolation of indoles with sodium trifluoromethanesulfinates in ionic liquids

An acid-promoted protocol has been developed to achieve the transition-metal- and phosphorus-free electrophilic trifluoromethylthiolation of indoles using sodium trifluoromethanesulfinates in an imidazolium-based ionic liquid ([Hmim]Br). [Hmim]Br not only acts as a recyclable solvent, but also as the reductant in this transformation. The advantages of this chemistry include simple operation, use of a recyclable solvent, avoidance of transition-metal and phosphorus, and gram-scale synthesis.