1517-59-5

Basic information

• Product Name: Benzenemethanol, 2-methyl-a-phenyl-, (S)-
• CAS NO: 1517-59-5
• Molecular Formula: C14H14O
• Molecular Weight: 198.265
• Mol File: 1517-59-5.mol
• Article Data: 109

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2-methyl-a-phenyl-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-methyl-a-phenyl-, (S)-(1517-59-5)
• EPA Substance Registry System: Benzenemethanol, 2-methyl-a-phenyl-, (S)-(1517-59-5)

Safety Data

• Hazardous Substances Data: 1517-59-5(Hazardous Substances Data)

Usage

Also known as

2-Methyl-2-phenyl-1-propanol, S-(+)-2-Methyl-2-phenyl-1-propanol
Organic compound
Commonly used in the production of pharmaceuticals and fragrances
Colorless liquid
Floral, rose-like odor
Used as a fragrance ingredient in perfumes, soaps, and personal care products
Used as a chiral auxiliary in asymmetric synthesis
Used as a chiral resolving agent for carboxylic acids
Potential applications in the production of pharmaceutical drugs and fine chemicals due to its chiral properties.

Upstream product

• 131-58-8 2-Methylbenzophenone 
• 529-20-4 2-methylphenyl aldehyde 
• 98-80-6 phenylboronic acid 
• 933-88-0 ortho-toluoyl chloride 
• 7294-50-0 tri-o-tolylboroxine 
• 100-52-7 benzaldehyde 
• 841-76-9 triphenylaluminium 
• 95-46-5 2-methylphenyl bromide 
• 90-02-8 salicylaldehyde 
• 81995-32-6 2-(i-butoxy)benzaldehyde 
• 1078-58-6 diphenylzinc 
• 5472-13-9 2-methylbenzhydrol 
• 91997-14-7 (methyl)(phenyl)zinc 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 33425-91-1 (R)-N,N-dimethyl-N-{2-[1-(2-methylphenyl)-1-phenylmethoxy]ethyl}amine 

Relevant articles and documents

Tridentate nitrogen phosphine ligand containing arylamine NH as well as preparation method and application thereof

The invention discloses a tridentate nitrogen phosphine ligand containing arylamine NH as well as a preparation method and application thereof, and belongs to the technical field of organic synthesis. The tridentate nitrogen phosphine ligand disclosed by the invention is the first case of tridentate nitrogen phosphine ligand containing not only a quinoline amine structure but also chiral ferrocene at present, a noble metal complex of the type of ligand shows good selectivity and extremely high catalytic activity in an asymmetric hydrogenation reaction, meanwhile, a cheap metal complex of the ligand can also show good selectivity and catalytic activity in the asymmetric hydrogenation reaction, and is very easy to modify in the aspects of electronic effect and space structure, so that the ligand has huge potential application value. A catalyst formed by the ligand and a transition metal complex can be used for catalyzing various reactions, can be used for synthesizing various drugs, and has important industrial application value.

Amino Acid-Functionalized Metal-Organic Frameworks for Asymmetric Base–Metal Catalysis

We report a strategy to develop heterogeneous single-site enantioselective catalysts based on naturally occurring amino acids and earth-abundant metals for eco-friendly asymmetric catalysis. The grafting of amino acids within the pores of a metal-organic framework (MOF), followed by post-synthetic metalation with iron precursor, affords highly active and enantioselective (>99 % ee for 10 examples) catalysts for hydrosilylation and hydroboration of carbonyl compounds. Impressively, the MOF-Fe catalyst displayed high turnover numbers of up to 10 000 and was recycled and reused more than 15 times without diminishing the enantioselectivity. MOF-Fe displayed much higher activity and enantioselectivity than its homogeneous control catalyst, likely due to the formation of robust single-site catalyst in the MOF through site-isolation.

Manganese catalyzed asymmetric transfer hydrogenation of ketones

The asymmetric transfer hydrogenation (ATH) of a wide range of ketones catalyzed by manganese complex as well as chiral PxNy-type ligand under mild conditions was investigated. Using 2-propanol as hydrogen source, various ketones could be enantioselectively hydrogenated by combining cheap, readily available [MnBr(CO)5] with chiral, 22-membered macrocyclic ligand (R,R,R',R')-CyP2N4 (L5) with 2 mol% of catalyst loading, affording highly valuable chiral alcohols with up to 95% ee.