15173-52-1Relevant articles and documents
-
v. Euw,Reichstein
, p. 1851,1853 (1944)
-
Absolute configuration at C(20) of the derivatives of 21-nor-5α-cholane-20,24-diol
Pouzar, Vladimir,Havel, Miroslav
, p. 2443 - 2451 (2007/10/02)
Derivatives of 21-nor-5α-cholane-20,24-diol XI and XIX were prepared by stepwise construction of the side-chain in the position 17β.Their absolute configuration at C(20) was determined on the basis of chemical correlation with the derivatives of 21-nor-5α-cholan-20-ol, XVI and XXIV.The absolute configuration of alcohols XVI and XXIV was determined from the ratio of the yields in which they are formed during the reduction of ketone X and using the benzoate rule.To compounds XI-XVIII the configuration 20R and to compounds XIX-XXVI the configuration 20S has been assigned.