15179-92-7Relevant articles and documents
TBAI or KI-Promoted Oxidative Coupling of Enamines and N-Tosylhydrazine: An Unconventional Method toward 1,5- and 1,4,5-Substituted 1,2,3-Triazoles
Huang, Wei,Zhu, Chuanle,Li, Minke,Yu, Yue,Wu, Wanqing,Tu, Zhengchao,Jiang, Huanfeng
supporting information, p. 3117 - 3123 (2018/08/01)
A novel method for the synthesis of 1,5- and 1,4,5-substituted 1,2,3-triazoles has been reported. This approach is promoted by iodine-TBHP oxidation system using enamines and N-tosylhydrazine as materials, which avoid the dependence of traditional methods on azides and transition metals. Through this approach, various 1,5- and 1,4,5-substituted 1,2,3-triazoles were delivered in moderate to high yields. The mechanistic study indicated that an amino exchange would be involved in the reaction process. Moreover, the product methyl 1-(2-methoxyphenyl)-4-methyl-1H-1,2,3-triazole-5-carboxylate is a useful precursor to anti-influenza A agent, and further application research was conducted. (Figure presented.).
A facile one-pot domino reaction for the stereoselective synthesis of acryl derivatives promoted by Ca(OTf)2
Yaragorla, Srinivasarao,Saini, Pyare Lal,Pareek, Abhishek,Almansour, Abdulrahman I.,Arumugam, Natarajan
supporting information, p. 2034 - 2038 (2016/04/26)
A facile one-pot domino reaction for the stereoselective synthesis of acryl derivatives has been reported using alkaline earth catalyst [Ca(OTf)2]. Initially aryl amine reacts with ethyl propiolate to form β-enamino ester which further reacts w
ENZYMATIC SYNTHESIS OF PROPARGYLAMIDES
Rebolledo, Francisca,Brieva, Rosario,Gotor, Vicente
, p. 5345 - 5346 (2007/10/02)
A lipase (Candida cylindracea) catalyzed the reaction between ethyl propiolate and aromatic amines to afford propargylamides.
