15180-00-4 Usage
Description
1,4-PREGNADIEN-11-BETA, 17,21-TRIOL-3,20-DIONE 17-VALERATE-21-ACETATE, also known as Prednival, is a synthetic glucocorticoid derived from the pregnane class of steroid hormones. It possesses potent anti-inflammatory and immunosuppressive properties, making it a valuable compound in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1,4-PREGNADIEN-11-BETA, 17,21-TRIOL-3,20-DIONE 17-VALERATE-21-ACETATE is used as a glucocorticoid for its anti-inflammatory and immunosuppressive effects. It is particularly useful in the treatment of various inflammatory and autoimmune disorders, such as rheumatoid arthritis, asthma, and allergies.
Used in Medical Research:
In the study of inflammation-inhibiting activity of steroids, Prednival has been utilized to investigate the potential of glucocorticoids in managing inflammation and related conditions. Its application in research helps to further understand the mechanisms of action and potential therapeutic benefits of glucocorticoids in various medical contexts.
Check Digit Verification of cas no
The CAS Registry Mumber 15180-00-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,8 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 15180-00:
(7*1)+(6*5)+(5*1)+(4*8)+(3*0)+(2*0)+(1*0)=74
74 % 10 = 4
So 15180-00-4 is a valid CAS Registry Number.
InChI:InChI=1/C26H36O6/c1-4-5-6-22(31)32-26(21(30)15-27)12-10-19-18-8-7-16-13-17(28)9-11-24(16,2)23(18)20(29)14-25(19,26)3/h9,11,13,18-20,23,27,29H,4-8,10,12,14-15H2,1-3H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1
15180-00-4Relevant articles and documents
Chemical synthesis technology for prednisolone valerate acetate
-
Paragraph 0049; 0053; 0054; 0058; 0062; 0063; 0067; 0071, (2019/04/26)
The invention belongs to the technical field of chemical synthesis, and discloses a chemical synthesis technology for prednisolone valerate acetate. With prednisolone, para-toluenesulfonic acid, trimethyl orthovalerate, dimethylaminopyridine, pyridine and acetic anhydride being raw materials, the prednisolone valerate acetate is synthesized through a few technological steps; in this way, the production process is simplified, production costs are remarkably lowered, the yield is high, product purity is high, and the chemical synthesis technology is suitable for large-scale production of factories, and has good industrial development value and good market application prospects.
An improved synthesis of corticosteroid 17α-esters by synthetic aluminium silicate-mediated conversion of 17α, 21-cyclic ortho esters
Sugai,Okazaki,Akaboshi
, p. 700 - 701 (2007/10/02)
-