15185-02-1

Basic information

• Product Name: BENZYL-ALPHA,ALPHA-D2-AMINE
• Synonyms: BENZYL-ALPHA,ALPHA-D2-AMINE;Benzyl-α-α-D2-amine;Benzyl-a,a-d2-aMine
• CAS NO: 15185-02-1
• Molecular Formula: C₇H₉N
• Molecular Weight: 109.17
• Mol File: 15185-02-1.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 63-65 °C(Press: 20 Torr)
• Appearance: /
• CAS DataBase Reference: BENZYL-ALPHA,ALPHA-D2-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL-ALPHA,ALPHA-D2-AMINE(15185-02-1)
• EPA Substance Registry System: BENZYL-ALPHA,ALPHA-D2-AMINE(15185-02-1)

Safety Data

• Hazardous Substances Data: 15185-02-1(Hazardous Substances Data)

Usage

Description

BENZYL-ALPHA,ALPHA-D2-AMINE, with the CAS number 15185-02-1, is an isotopically labeled research compound that is utilized in various scientific studies and experiments. It is a derivative of benzylamine, where the hydrogen atoms are replaced with deuterium atoms, making it a valuable tool for researchers to investigate the properties and behavior of molecules in different conditions.

Uses

Used in Research and Development:
BENZYL-ALPHA,ALPHA-D2-AMINE is used as an isotopically labeled compound for [application reason] in the field of research and development. The presence of deuterium atoms in the molecule allows researchers to study the effects of isotopic substitution on the compound's chemical and physical properties, as well as its interactions with other molecules and biological systems.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, BENZYL-ALPHA,ALPHA-D2-AMINE is used as a research compound for [application reason] in the development of new drugs and therapies. The isotopically labeled nature of the compound can help researchers understand the metabolic pathways and pharmacokinetics of similar molecules, ultimately leading to the design of more effective and safer drugs.
Used in Chemical Industry:
BENZYL-ALPHA,ALPHA-D2-AMINE is used as a labeled compound for [application reason] in the chemical industry. It can be employed in the synthesis of other isotopically labeled compounds, which can then be used in various applications, such as in the study of reaction mechanisms, catalysis, and the development of new materials.
Used in Environmental Science:
In environmental science, BENZYL-ALPHA,ALPHA-D2-AMINE is used as a tracer compound for [application reason] in the study of the fate and transport of pollutants in the environment. The use of isotopically labeled compounds allows researchers to track the movement and transformation of these pollutants in various environmental matrices, such as soil, water, and air.
Used in Analytical Chemistry:
BENZYL-ALPHA,ALPHA-D2-AMINE is used as a reference material for [application reason] in analytical chemistry. The compound can be used to calibrate and validate analytical instruments and methods, ensuring the accuracy and reliability of measurements in various fields, including pharmaceutical, chemical, and environmental analysis.

Upstream product

• 100-47-0 benzonitrile 
• 55-21-0 benzamide 
• 51271-29-5 [1',1'-2H₂]benzyl bromide 
• 93-89-0 benzoic acid ethyl ester 
• 21175-64-4 1,1-dideuteriophenylmethanol 

Downstream Products

• 85013-33-8 <1-2H2>benzyl-p-nitrophenyltriazene 
• 122821-76-5 N-(2,2-dichloro-1-phenylcyclopropylmethylene)-α,α-dideuteriobenzylamine 
• 21175-64-4 1,1-dideuteriophenylmethanol 
• 33712-34-4 benzyl-d2 chloride 
• 107135-08-0 α-deuteriophenyldiazomethane 
• 50848-70-9 acetoxy-dideuterio-phenyl-methane 
• 20002-22-6 dibenzylamine-α,α,α',α'-d4 
• 20002-23-7 N-nitroso<α,α,α'α'-2H4>dibenzylamine 
• 4397-68-6 α-deutero benzylamine 
• 100-46-9 benzylamine 
• 134080-36-7 dibenzylamine-α,α'-d₂ 
• 103-49-1 dibenzylamine 
• 82679-51-4 N-(p-methoxybenzylidene)-α,α-dideuteriobenzylamine 
• 37825-94-8 (α-(2)H)benzyl acetate 

Relevant articles and documents

Preparation of deuteriated benzylamines and phenethylamine with Raney alloys in an alkaline deuterium oxide solution

Benzyl-α,α-2H2-amine, 2-2H1-Benzyl-α,α-2H2-amine, 3-2H1-Benzyl-α,α-2H2-amine, 4-2H1-Benzyl-α,α-2H2-am

Rhodium-Catalyzed Intramolecular C-H Bond Activation with Triazoles: Preparation of Stereodefined Pyrrolidines and Other Related Cyclic Compounds

On treatment of triazoles having an N-sulfonyl-protected benzylamine moiety with [Rh2(C7H15CO2)4], intramolecular C-H bond insertion takes place at the benzylic position to give cis-N-sulfonyl-2-aryl-3-[(sulfonylimino)methyl]pyrrolidines in good yields and with highly stereoselectivities. Analogously, the similar treatment of triazoles having an ether or even an alkyl moiety affords 2-alkyl- or 2-aryl-3-[(sulfonylimino)methyl]tetrahydrofurans or a 2-alkyl-3-[(sulfonylimino)methyl]cyclopentane in good yields. Three is a magic number: On treatment of triazoles with [Rh2(C7H15CO2)4], the rhodium catalyst plays three roles, denitrogenation, C-H bond activation, and stereoselective cyclization, providing a new method for heterocycle synthesis. Intramolecular C-H bond insertion takes place at the benzylic position to give pyrrolidines and related heterocycles in good yields.

Catalytic Amine Oxidation under Ambient Aerobic Conditions: Mimicry of Monoamine Oxidase B

The flavoenzyme monoamine oxidase (MAO) regulates mammalian behavioral patterns by modulating neurotransmitters such as adrenaline and serotonin. The mechanistic basis which underpins this enzyme is far from agreed upon. Reported herein is that the combination of a synthetic flavin and alloxan generates a catalyst system which facilitates biomimetic amine oxidation. Mechanistic and electron paramagnetic (EPR) spectroscopic data supports the conclusion that the reaction proceeds through a radical manifold. This data provides the first example of a biorelevant synthetic model for monoamine oxidase B activity.