1519103-09-3

Basic information

• Product Name: N-4-toluenesulfonyl-(E)-3-cyclohexylprop-2-enamide
• Synonyms: N-4-toluenesulfonyl-(E)-3-cyclohexylprop-2-enamide
• CAS NO: 1519103-09-3
• Molecular Weight: 307.414
• Mol File: 1519103-09-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-4-toluenesulfonyl-(E)-3-cyclohexylprop-2-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-4-toluenesulfonyl-(E)-3-cyclohexylprop-2-enamide(1519103-09-3)
• EPA Substance Registry System: N-4-toluenesulfonyl-(E)-3-cyclohexylprop-2-enamide(1519103-09-3)

Safety Data

• Hazardous Substances Data: 1519103-09-3(Hazardous Substances Data)

Upstream product

• 941-55-9 4-toluenesulfonyl azide 
• 108104-21-8 1-cyclohexylprop-2-yn-1-yl acetate 

Relevant articles and documents

Cu-catalyzed conversion of propargyl acetates to e-a,β-unsaturated amides via ketenimine formation with sulfonyl azides

The reaction between readily accessible propargyl acetates and sulfonyl azides in the presence of CuI catalyst yields trans-a,β-unsaturated Ntosylamides via N-sulfonyl ketenimine formation followed by a probable 1,3- OAc migration ([3,3]-sigmatropic rearrangement). The reaction is very general, allowing all kinds of substitution, including alkyl, aryl (electrondonating, -withdrawing, and -neutral), heteroaryl, and vinyl groups, on the Cterminal of acrylamide. Also, the method affords the products at ambient temperature with excellent diastereoselectivity in moderate to good yields.