151914-79-3

Basic information

• Product Name: methyl 1-(3-tert-butyl-1H-pyrazol-5-yl)-1H-1,2,3-triazole-4-carboxylate
• Synonyms: methyl 1-(3-tert-butyl-1H-pyrazol-5-yl)-1H-1,2,3-triazole-4-carboxylate
• CAS NO: 151914-79-3
• Molecular Weight: 249.272
• Mol File: 151914-79-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 1-(3-tert-butyl-1H-pyrazol-5-yl)-1H-1,2,3-triazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-(3-tert-butyl-1H-pyrazol-5-yl)-1H-1,2,3-triazole-4-carboxylate(151914-79-3)
• EPA Substance Registry System: methyl 1-(3-tert-butyl-1H-pyrazol-5-yl)-1H-1,2,3-triazole-4-carboxylate(151914-79-3)

Safety Data

• Hazardous Substances Data: 151914-79-3(Hazardous Substances Data)

Upstream product

• 82560-12-1 3-tert-butyl-1H-pyrazole-5-amine 
• 14762-48-2 ethyl 2-diazo-3-oxo-propanoate 

Relevant articles and documents

Preparation and pyrolysis of 1-(pyrazol-5-yl)-1,2,3-triazoles and related compounds

1-(Pyrazol-5-yl)-1,2,3-triazoles 8a, 9a and 10 are prepared by cycloaddition of 5-azidopyrazoles with methyl prop-2-ynoate. The regiochemistry of the process is confirmed by synthesis of 9a using an authentic route from ethyl 2-formyl-2-diazoacetate 13. Flash vacuum pyrolysis of 8a, 9a and 10 gives 5-methoxypyrazolo[1,5-a]pyrimidin-7-ones 16-18 by a mechanism involving an unexpected oxoketenimineimidoyl ketene rearrangement as the key step. The mechanism is supported by a 13C labelling experiment. A general route to pyrazolo[1,5-a]pyrimidin-7-ones from pyrazolylaminomethylene Meldrum's acid derivatives (e.g. 30-32) is also reported.