1520087-46-0

Basic information

• Product Name: 2-(4-chlorophenyl)-4-(p-tolyl)quinazoline
• Synonyms: 2-(4-chlorophenyl)-4-(p-tolyl)quinazoline
• CAS NO: 1520087-46-0
• Molecular Weight: 330.816
• Mol File: 1520087-46-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)-4-(p-tolyl)quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-4-(p-tolyl)quinazoline(1520087-46-0)
• EPA Substance Registry System: 2-(4-chlorophenyl)-4-(p-tolyl)quinazoline(1520087-46-0)

Safety Data

• Hazardous Substances Data: 1520087-46-0(Hazardous Substances Data)

Upstream product

• 7455-77-8 2-(4-chlorophenyl)-4(3H)-quinazolinone 
• 5720-05-8 4-methylphenylboronic acid 
• 5439-98-5 2-phenyl-2,3-dihydro-phthalazine-1,4-dione 
• 4294-57-9 para-methylphenylmagnesium bromide 

Relevant articles and documents

Ru(II)-Catalyzed C-H Activation and Annulation Reaction via Carbon-Carbon Triple Bond Cleavage

An unprecedented Ru(II)-catalyzed C-H activation and annulation reaction, which proceeds via C-C triple bond cleavage, is reported. This reaction of 2-phenyldihydrophthalazinediones with alkynes, which works most efficiently in the presence of bidented ligand 1,3-bis(diphenylphosphino)propane, affords good yields of substituted quinazolines.

Nickel-catalyzed Kumada Cross-coupling Reaction for the Synthesis of 2,4-Diarylquinazolines

A series of 2,4-diarylquinazolines have been successfully synthesized via the Ni-catalyzed cross-coupling reaction of quinazoline-4-tosylates and aryl Grignard reagents, which provided alternative straightforward approaches for the introduction of aryl groups to quinazolines at C-4 position.