1520120-86-8

Basic information

• Product Name: benzyl (1R,2R)-2-carbamoylcyclopropanecarboxylate
• Synonyms: benzyl (1R,2R)-2-carbamoylcyclopropanecarboxylate
• CAS NO: 1520120-86-8
• Molecular Weight: 219.24
• Mol File: 1520120-86-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl (1R,2R)-2-carbamoylcyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (1R,2R)-2-carbamoylcyclopropanecarboxylate(1520120-86-8)
• EPA Substance Registry System: benzyl (1R,2R)-2-carbamoylcyclopropanecarboxylate(1520120-86-8)

Safety Data

• Hazardous Substances Data: 1520120-86-8(Hazardous Substances Data)

Upstream product

• 35974-55-1 methyl (±)-trans-2-carbamoylcyclopropanecarboxylate 
• 3999-55-1 diethyl trans-cyclopropane-1,2-dicarboxylate 
• 826-35-7 dimethyl trans-1,2-cyclopropanedicarboxylate 
• 100-51-6 benzyl alcohol 
• 13279-88-4 racemic trans-2-methoxycarbonylcyclopropanecarboxylic acid 

Relevant articles and documents

Enantioselective bacterial hydrolysis of amido esters and diamides derived from (±)-trans-cyclopropane-1,2-dicarboxylic acid

Different optically active amido esters, mixed acid esters, amido acids, and diamides derived from trans-cyclopropane-1,2-dicarboxylic acid were prepared from the commercially available diethyl (±)-trans-cyclopropane-1,2- dicarboxylate. The key step was the Rhodococcus rhodochrous IFO 15564 catalyzed hydrolysis of the corresponding racemic amide. The amidase present in this microorganism showed moderate to high enantioselectivity towards these substrates. In addition a simple and efficient Curtius rearrangement of some of the enzymatically prepared cyclopropanecarboxylic acids allowed us to obtain optically active β-aminocyclopropanecarboxylic acid derivatives with high yields and enantiomeric excesses. The Royal Society of Chemistry.