15222-36-3Relevant articles and documents
Green Access to α-Haloalkyl and α-Halobenzyl Esters, Versatile Intermediates for the One-Pot Two-Step Synthesis of O, O ′-Diacyl Acetals Using Zinc-Based Ionic Liquid Catalyst
Fache, Fabienne,De Azpiazu, Ignasi,Pelotier, Béatrice,Piva, Olivier,Gozzi, Christel
, p. 2430 - 2434 (2019/05/27)
α-Haloalkyl and α-halobenzyl esters have been synthesized using a zinc-based ionic liquid catalyst, BMIZnCl 3. These esters can then react with acids without intermediate purification to obtain mixed O, O ′-diacyl acetals in a one-pot process.
Zn(OTf)2.6H2O catalysed acylation of aldehydes: Preparation of 1,1-diacetates and α-chloroalkyl esters
Su, Weike,Can, Jin
, p. 88 - 90 (2007/10/03)
1,1-Diacetates (acylals) and α-chloroalkyl esters were prepared from carbonyl compounds with acylating reagents in the presence of 5% mol hexaaqua zinc triflate [Zn(OTf)2.6H2O] with good yields under mild reaction conditions.
N-heteroarylium Salts in Synthesis, 3 Intramolecular ortho-Acylation of Some N-Heteroaromatic Ring Systems
Anders, Ernst,Boldt, Hans Guenter,Clark, Timothy,Fuchs, Renate,Gassner, Thomas
, p. 279 - 296 (2007/10/02)
The title compounds 17 (prepared by methods A-C) have been reacted with sodium bis(trimethylsilyl)amide (18) in a heterogeneous mixture (-80 deg C, 2-60 h).The ortho-substituted N-heteroaromatic compounds 4 are isolated exclusively after an intramolecular and regiospecific reaction .This method represents the first widely applicable acylation technique for N-heteroaromatic compounds in which the incoming substituent (R1CO) functions as an internal electrophile and in which the formation of isomeric or polyacylated products has not yet been observed.Both experimental and theoretical (MNDO) investigations show that the substitution reaction (5) is primarily determined by the conformational and electronic properties of the deprotonation product 25 , which is formed preferentially.