152253-24-2Relevant articles and documents
PROTEASE-CATALYZED ENANTIOSELECTIVE SYNTHESIS OF OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINES
Hirose, Yoshihiko,Kariya, Kinya,Sasaki, Ikuharu,Kurono, Yoshiaki,Achiwa, Kazuo
, p. 3441 - 3444 (2007/10/02)
The first enantioselective protease-catalyzed hydrolyses of 1,4-dihydropyridine-3,5-dicarboxylic diesters were developed.The monoesters obtained had high optical purity and were useful building blocks which could easily lead to optically active Ca-blockers.