1524-12-5Relevant articles and documents
Efficient photolytic C-H bond functionalization of alkylbenzene with hypervalent iodine(iii) reagent
Sakamoto, Ryu,Inada, Tsubasa,Selvakumar, Sermadurai,Moteki, Shin A.,Maruoka, Keiji
supporting information, p. 3758 - 3761 (2016/03/25)
A practical approach to radical C-H bond functionalization by the photolysis of a hypervalent iodine(iii) reagent is presented. The photolysis of [bis(trifluoroacetoxy)iodo]benzene (PIFA) leads to the generation of trifluoroacetoxy radicals, which allows the smooth transformation of various alkylbenzenes to the corresponding benzyl ester compounds under mild reaction conditions.
β-aryl nitrile construction via palladium-catalyzed decarboxylative benzylation of α-cyano aliphatic carboxylate salts
Shang, Rui,Huang, Zheng,Xiao, Xiao,Lu, Xi,Fu, Yao,Liu, Lei
supporting information, p. 2465 - 2472,8 (2020/08/31)
The palladium-catalyzed decarboxylative benzylation of α-cyano aliphatic carboxylate salts with benzyl electrophiles was discovered. This reaction exhibits good functional group compatibility and proceeds under relatively mild conditions. A diverse range of quaternary, tertiary and secondary β-aryl nitriles can be conveniently prepared by this method. Copyright
Improved procedure for the reductive acetylation of acyclic esters and a new synthesis of ethers
Kopecky, David J.,Rychnovsky, Scott D.
, p. 191 - 198 (2007/10/03)
An optimized protocol for the DIBALH reductive acetylation of acyclic esters and diesters is described. This reductive acetylation procedure allows a wide variety of esters to be converted into the corresponding α-acetoxy ethers in good to excellent yields. It was found that, under mild acidic conditions, many α-acetoxy ethers can be further reduced to the corresponding ethers. This net two-step ester deoxygenation is an attractive alternative to the classical Williamson synthesis for certain ethers.
