152510-47-9Relevant articles and documents
Large Scale Synthesis of an Ampakine-type Active Pharmaceutical Ingredient Based on a Telescoped Regioselective Double Amidation Reaction
Hardouin, Christophe,Pin, Frédéric,Giffard, Jean-Fran?ois,Hervouet, Yvon,Hublet, Julie,Janvier, Solenn,Penloup, Christine,Picard, Julien,Pinault, Nathalie,Schiavi, Bruno,Zhang, Peng,Zhao, Weiwei,Zhu, Xueyan
, p. 1932 - 1947 (2019/10/11)
This work describes the process development and manufacture of an ampakine-type active pharmaceutical ingredient in clinical trials. A regioselective CDI-mediated amidation process was optimized for the subsequent couplings of two distinctive amines with
An Unusual Intramolecular Aromatic Nucloephilic Addition to an Activated Diazonium Salt
Panetta, Charles A.,Fang, Zheng,Heimer, Norman E.
, p. 6146 - 6147 (2007/10/02)
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