152538-73-3 Usage
Description
(2,2,2-Trifluoroethoxy)difluoroacetic acid is a chemical compound characterized by its fluorinated structure, which consists of a difluoroacetic acid backbone with a 2,2,2-trifluoroethoxy group attached. (2,2,2-Trifluoroethoxy)difluoroacetic acid is known for its unique properties and reactivity, making it a valuable intermediate in the synthesis of various pharmaceuticals and other specialty chemicals.
Uses
Used in Pharmaceutical Industry:
(2,2,2-Trifluoroethoxy)difluoroacetic acid is used as a key intermediate in the synthesis of enantiomers of Isoflurane, which is an inhalation anesthetic agent. Isoflurane is widely used in medical and veterinary applications for its rapid onset, stable anesthesia, and minimal side effects. The compound's role in the preparation of Isoflurane enantiomers highlights its importance in the development of effective and safe anesthetics.
Additionally, due to its fluorinated nature, (2,2,2-Trifluoroethoxy)difluoroacetic acid may have potential applications in other industries, such as in the development of advanced materials with specific properties or in the synthesis of other fluorinated compounds with various applications. However, further research and development would be required to explore these potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 152538-73-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,5,3 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 152538-73:
(8*1)+(7*5)+(6*2)+(5*5)+(4*3)+(3*8)+(2*7)+(1*3)=133
133 % 10 = 3
So 152538-73-3 is a valid CAS Registry Number.
152538-73-3Relevant articles and documents
Preparation of the Isoflurane Enantiomers
Huang, Chialang G.,Rozov, Leonid A.,Halpern, Donald F.,Vernice, Gerald G.
, p. 7382 - 7387 (1993)
The enantiomers of the inhalation anesthetic agent, isoflurane (1-chloro-2,2,2-trifluoroethyl difluoromethyl ether), are prepared by a synthesis starting from 2,2,2-trifluoroethanol. (R)-(+)-Dehydroabietylamine is used as the resolving agent for the racemic acid intermediate 1.The optical purities of both (S)-(+)- and (R)-(-)-isofluranes are determined to be >99percent ee (enantiomeric excess) by chiral capillary gas chromatography.
