152614-95-4

Basic information

• Product Name: BOC-pseudoephedrine
• Synonyms: BOC-pseudoephedrine
• CAS NO: 152614-95-4
• Molecular Weight: 265.353
• Mol File: 152614-95-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: BOC-pseudoephedrine(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-pseudoephedrine(152614-95-4)
• EPA Substance Registry System: BOC-pseudoephedrine(152614-95-4)

Safety Data

• Hazardous Substances Data: 152614-95-4(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 345-78-8 Novafed 

Downstream Products

• 16251-47-1 (4S,5S)-3,4-dimethyl-5-phenyl-1,3-oxazolidin-2-one 
• 16251-46-0 (4S,5R)-3,4-dimethyl-5-phenyl-1,3-oxazolidin-2-one 
• 5411-22-3 benzfetamine hydrochloride 
• 6192-97-8 (S)-1-cyclohexyl-N-methylpropan-2-amine 
• 51-57-0 S-methamphetamine hydrochloride 
• 156-08-1 benzphetamine 
• 1334921-74-2 C₁₅H₂₃NO₂ 
• 1591761-32-8 (S)-N-benzyl-1-cyclohexyl-N-methylpropan-2-amine hydrochloride 

Relevant articles and documents

An efficient, scalable process for benzphetamine hydrochloride

Commercial manufacturing of benzphetamine hydrochloride along with its impurity profiling is disclosed. Deoxygenation of pseudoephedrine is reported with ～100% retention by shielding the amine group as its tert-butyl carbamate, which is very straightforward to eliminate at the end. Four unknown process-related impurities are isolated from the samples of final API and characterized on the basis of their NMR and mass spectral analysis. Structures of the isolated impurities are confirmed by independent syntheses and coinjecting with the isolated one.