152628-30-3

Basic information

• Product Name: 3-Iod-N-methyl-4-tosyloxy-chinolin-2(1H)-on
• Synonyms: 3-Iod-N-methyl-4-tosyloxy-chinolin-2(1H)-on
• CAS NO: 152628-30-3
• Molecular Weight: 455.273
• Mol File: 152628-30-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Iod-N-methyl-4-tosyloxy-chinolin-2(1H)-on(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Iod-N-methyl-4-tosyloxy-chinolin-2(1H)-on(152628-30-3)
• EPA Substance Registry System: 3-Iod-N-methyl-4-tosyloxy-chinolin-2(1H)-on(152628-30-3)

Safety Data

• Hazardous Substances Data: 152628-30-3(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 98751-17-8 4-hydroxy-3-iodo-1-methyl-1,2-dihydroquinolin-2-one 

Downstream Products

• 1677-46-9 4-hydroxy-1-methyl-2(1H)-quinolone 
• 649-15-0 N,N-diethyl-4-methylbenzenesulfonamide 
• 110229-40-8 4-(p-toluenesulfonyloxy)-1-methyl-quinolin-2(1H)-one 

Relevant articles and documents

Heck reactions of 3-iodo-N-methyl-quinolin-2(1H)-ones with 2-methylbut-3-en-2-ol

Treatment of 4-acetoxy-3-iod-N-methyl-quinolin-2(1H)-one, 3-iod-N-methyl-4-tosyloxy-quinolin-2(1H)-one and 3-iod-4-methoxy-N-methyl-quinolin-2(1H)-one with 2-methylbut-3-en-2-ol under Heck conditions led to the related (E)-3-(3-methylbut-1-en-3-olyl)-derivatives, potential precursors of dimeric quinolines. Dehydration of the tertiary hydroxy group of 4-methoxy-(E)-3-(3-methylbut-1-en-3-olyl)-N-methyl-quinolin-2(1H)-one with acetic acid gave 4-methoxy-(E)-3-(3-methylbut-1,3-dienyl)-N-methyl-quinolin-2(1H)-one.